FLAAS
Adenosine 5′-triphosphate (ATP) disodium salt hydrate
≥90%, bacterial (Corynebacterium sp), lyophilized powder
동의어(들):
ATP disodium hydrate
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
C10H14N5O13P3Na2 · xH2O
CAS 번호:
Molecular Weight:
551.14 (anhydrous basis)
eCl@ss:
32160414
PubChem Substance ID:
NACRES:
NA.26
EC Number:
213-579-1
MDL number:
UNSPSC Code:
12352208
Assay:
≥90%
Biological source:
bacterial (Corynebacterium sp)
Form:
lyophilized powder
Solubility:
water: soluble, clear, colorless (1 vial + 0.1 mL)
Storage temp.:
−20°C
제품 이름
Adenosine 5′-triphosphate (ATP) disodium salt hydrate, vial of ~1 mg ATP
SMILES string
Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O
InChI
1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1
InChI key
NTBQNWBHIXNPRU-MSQVLRTGSA-L
biological source
bacterial (Corynebacterium sp)
assay
≥90%
form
lyophilized powder
packaging
vial of ~1 mg ATP
solubility
water: soluble, clear, colorless (1 vial + 0.1 mL)
storage temp.
−20°C
Quality Level
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Application
Adenosine 5′-triphosphate (ATP) disodium salt hydrate has been:
- used as a standard to measure ATP by bioluminescence method
- used in kinase buffer to assess the interaction between death-associated protein kinases (DAPK2) and 14-3-3-β
- used as a standard in ATP colorimetric assay
Biochem/physiol Actions
Adenosine 5′-triphosphate (ATP) is one of the nucleoside triphosphate present in living system. It controls various biologic processes such as glucose metabolism, muscle contraction and neurotransmission. Apart from this, ATP serves as an important energy source for the cell. Administration of ATP might be useful in the treatment of non-small-cell lung cancer.
Adenosine 5′-triphosphate was shown to have inhibitory effects on the inflammatory response by abrogating secretion of TNF-α and promoting secretion of Interleukin-10.
P2 purinergic agonist; increases activity of Ca2+-activated K+ channels; substrate for ATP-dependent enzyme systems
Preparation Note
Each vial contains ~1.2 mg of Na2ATP • 3H2O equivalent to ~1.0 mg of ATP (2.0 μmol). Actual amount printed on the label.
Prepared to be substantially vanadium-free.
저장 등급
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Identification of novel death-associated protein kinase 2 interaction partners by proteomic screening coupled with bimolecular fluorescence complementation
Geering B, et al.
Molecular and Cellular Biology, 36(1), 132-143 (2016)
Jie Ge et al.
Journal of medicinal chemistry, 49(15), 4606-4615 (2006-07-21)
17-Allylamino-17-demethoxygeldanamycin (17-AAG)1 is a semisynthetic inhibitor of the 90 kDa heat shock protein (Hsp90) currently in clinical trials for the treatment of cancer. However, 17-AAG faces challenging formulation issues due to its poor solubility. Here we report the synthesis and
Els L R Swennen et al.
European journal of immunology, 35(3), 852-858 (2005-02-19)
In vitro studies suggest that extracellular nucleotides and nucleosides may be important regulators of inflammatory and immune responses. Most studies with adenosine 5'-triphosphate (ATP) have been performed in cell lines, which are remote from the human situation. The purpose of
Randomized clinical trial of adenosine 5?-triphosphate in patients with advanced non-small-cell lung cancer
Agteresch HJ, et al.
Journal of the National Cancer Institute, 92(4), 321-328 (2000)
관련 콘텐츠
Instructions
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