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Merck

G2262

γ-Glutamyltranspeptidase from porcine kidney

Type IV, 2.0-6.0 units/mg solid

동의어(들):

γ-GT, γ-Glutamyltransferase, (5-Glutamyl)peptide:amino-acid 5-glutamyltransferase, GGTP

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제품정보 (DICE 배송 시 비용 별도)

CAS 번호:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
232-931-5
MDL number:
EC 번호:
Specific activity:
2.0-6.0 units/mg solid
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도움 문의

Quality Level

type

Type IV

form

powder

specific activity

2.0-6.0 units/mg solid

storage temp.

−20°C

Application

γ-Glutamyltranspeptidase is used in the food industry to improve the umami taste of soy sauce.

Biochem/physiol Actions

γ- Glutamyltranspeptidase cleaves theγ-glutamyl amide bond from glutathione and its S-conjugates to remove glutamate.

Analysis Note

Crude

Other Notes

One unit will liberate 1.0 μmole of p-nitroaniline from L-γ-glutamyl-p-nitroanilide per min at pH 8.5 at 25°C.

저장 등급

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

Improving the umami taste of soy sauce by the addition of bacterial γ-glutamyltranspeptidase as a glutaminase to the fermentation mixture
K. Kijima & H. Suzuki
Enzyme and Microbial Technology, 41, 80-84 (2007)
S S Tate et al.
Molecular and cellular biochemistry, 39, 357-368 (1981-09-25)
gamma-Glutamyl transpeptidase catalyzes transfer of the gamma-glutamyl moiety of glutathione to amino acids, dipeptides, and to glutathione itself; the enzyme also catalyzes the hydrolysis of glutathione to glutamate and cysteinyl-glycine. This review deals with the tissue distribution and localization of
Stephanie Wickham et al.
The Biochemical journal, 450(3), 547-557 (2013-01-11)
GGT (γ-glutamyl transpeptidase) is an essential enzyme for maintaining cysteine homoeostasis, leukotriene synthesis, metabolism of glutathione conjugates and catabolism of extracellular glutathione. Overexpression of GGT has been implicated in many pathologies, and clinical inhibitors of GGT are under development for
γ-Glutamyl transferase and its role as a biomarker of systemic malignancies other than hepatocellular carcinomas.
Shailendra Kapoor
European journal of gastroenterology & hepatology, 25(3), 387-387 (2013-01-26)
Mathias Oertli et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(8), 3047-3052 (2013-02-06)
Infection with the gastric bacterial pathogen Helicobacter pylori is typically contracted in early childhood and often persists for decades. The immunomodulatory properties of H. pylori that allow it to colonize humans persistently are believed to also account for H. pylori's

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