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Merck

G5502

Guaiacol

oxidation indicator

동의어(들):

2-Methoxyphenol, Catechol monomethyl ether, Pyrocatechol monomethyl ether

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
(CH3O)C6H4OH
CAS 번호:
Molecular Weight:
124.14
UNSPSC Code:
12352202
NACRES:
NA.77
PubChem Substance ID:
EC Number:
201-964-7
Beilstein/REAXYS Number:
508112
MDL number:
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vapor density

4.27 (vs air)

Quality Level

vapor pressure

0.11 mmHg ( 25 °C)

assay

≥98.0%

form

liquid, solid

refractive index

n20/D 1.543 (lit.)

bp

205 °C (lit.)

mp

26-29 °C (lit.)

density

1.129 g/mL at 25 °C (lit.)

SMILES string

COc1ccccc1O

InChI

1S/C7H8O2/c1-9-7-5-3-2-4-6(7)8/h2-5,8H,1H3

InChI key

LHGVFZTZFXWLCP-UHFFFAOYSA-N

General description

Guaiacol, a phenolic compound, acts as a scavenger of superoxide radicals. It is produced from guaiacum or wood creosote. Guaiacol acts as a precursor to different favoring agents like, vanillin and roasted coffee. It is used as an antiseptic, analgesic and sedative drug for the treatment of dental pulp and periodontal tissue. Guaiacol enhances cell proliferation in vivo.

Application

Guaiacol has been used:
  • as a substrate for peroxidase enzyme to determine its activity
  • as a substrate to determine laccase activity
  • as a reagent in peroxidase (POD) activity test

Biochem/physiol Actions

Guaiacol, along with 2,4,6-trichloroanisole, is responsible for cork taint in wine. A method has been developed for extraction and quantitation of the two compounds.
Guaiacol has an ability to inhibit prostaglandin biosynthesis, without causing damage to the gastrointestinal system, unlike classic NSAID (nonsteroidal anti-inflammatory drugs).

Disclaimer

May be liquid at room temperature.


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Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

저장 등급

11 - Combustible Solids

wgk

WGK 1

flash_point_f

194.0 °F - closed cup

flash_point_c

90 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves



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관련 콘텐츠

Product Information Sheet


Constituent profiles
Essential Oil Safety-A Guide for Health Care Professionals (2014)
Increased Levels of Antinutritional and/or Defense Proteins Reduced the Protein Quality of a Disease-Resistant Soybean Cultivar
Sousa DOB, et al.
Nutrients, 7(7), 6038-6054 (2015)
Thermal preference ranges correlate with stable signals of universal stress markers in Lake Baikal endemic and Holarctic amphipods
Axenov-Gribanov D, et al
PLoS ONE, 11(10), e0164226-e0164226 (2016)