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Merck

G8540

L-Glutamine

99.0-101.0%, suitable for cell culture, non-animal source, meets USP testing specifications

동의어(들):

(S)-2,5-Diamino-5-oxopentanoic acid, L-Glutamic acid 5-amide, Levoglutamide

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
H2NCOCH2CH2CH(NH2)CO2H
CAS 번호:
56-85-9
Molecular Weight:
146.14
MDL number:
MFCD00008044
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24895342
NACRES:
NA.26
EC Number:
200-292-1
Beilstein/REAXYS Number:
1723797

주요 문서

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제품 이름

L-Glutamine, meets USP testing specifications, suitable for cell culture, 99.0-101.0%, from non-animal source

SMILES string

N[C@@H](CCC(N)=O)C(O)=O

InChI key

ZDXPYRJPNDTMRX-VKHMYHEASA-N

InChI

1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1

biological source

non-animal source

agency

meets USP testing specifications

assay

99.0-101.0%

form

powder

optical activity

[α]20/D 31.5 to 33.0°, c = 10 in 2 M HCl
[α]20/D 6.3 to 7.3°, c = 4 in water

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, residual solvents, tested

ign. residue

≤0.10%

loss

≤0.30% loss on drying

color

white

mp

185 °C (dec.) (lit.)

solubility

H2O: 25 mg/mL

anion traces

chloride (Cl-): ≤0.020%
sulfate (SO42-): ≤0.020%

cation traces

As: ≤1 ppm
Fe: ≤10 ppm
NH4+: ≤0.10%

application(s)

agriculture

functional group

amide

storage temp.

room temp

Quality Level

300

Gene Information

rat ... Ggt1(116568)

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관련 카테고리

Application

L-Glutamine amino acid has been used:

  • as a component of the serum-free medium to culture mice cochlear organotypic cells.
  • as a supplement in Dulbecco′s modified Eagle′s medium-nutrient mixture F-12 (DMEM/F-12) medium for culturing mice seminiferous tubule segments.
  • as a supplement in Roswell Park Memorial Institute (RPMI) 1640 medium to culture human monocytic cell line.

Biochem/physiol Actions

L-Glutamine is an essential amino acid that is a crucial component of culture media that serves as a major energy source for cells in culture. L-Glutamine is very stable as a dry powder and as a frozen solution. In liquid media or stock solutions, however, L-glutamine degrades relatively rapidly. Optimal cell performance usually requires supplementation of the media with L-glutamine prior to use.
L-Glutamine or Glutamine powder serves as a precursor for the synthesis of peptides, proteins, nucleotides, purine, pyrimidine, amino sugars, and nucleic acids. It plays an important role in promoting and maintaining cellular functions. Many cells and tissues like the intestine, kidneys, neurons in the central nervous system (CNS), liver, and pancreatic β-cells utilize glutamine at higher levels for their functioning. Glutamine regulates acid-base homeostasis and catabolic signaling. Glutamine plays a vital role in nitrogen transport and maintains the cellular redox state.Glutamine provides the necessary nitrogen, carbon and the reducing equivalents required for cell growth and division during cell culture. L-glutamic acid aids the incorporation of NH4+ into biomolecules.

General description

L-Glutamine is the most abundant amino acid in mammalian blood and tissues. It is vital for biochemical and cell culture research. It supports cell growth, metabolism, and protein synthesis. In cell culture, it ensures cell viability, proliferation, and antibody production. In biochemical studies, L-Glutamine aids in metabolic pathways, biomolecule synthesis, and cellular processes.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research
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저장 등급

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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시험 성적서(COA)

Lot/Batch Number
0000514825
0000514824
0000514823
0000514823
0000514824

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Glutamine and glutamate?their central role in cell metabolism and function
Newsholme P, et al.
Cell Biochemistry and Function, 21(1) (2003)
Curcumin Alters Neural Plasticity and Viability of Intact Hippocampal Circuits and Attenuates Behavioral Despair and COX-2 Expression in Chronically Stressed Rats
Ga-Young Choi
Mediators of Inflammation (2017)
Nuclear Transfer into Mouse Oocytes
Journal of Visualized Experiments, 1, 116-116 (2006)
Interleukin-6 and IL-6 receptor cell expression in testis of rats with autoimmune orchitis
Rival C, et al.
Journal of Reproductive Immunology, 70(1-2), 43-58 (2006)
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Science, 324(5930), 1029?1033-1029?1033 (2009)
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L-Glutamine in Cell Culture

Importance and uses of glutamine in hybridoma and mammalian cell culture

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