H7250

Histamine dihydrochloride

Name: Histamine dihydrochloride
Brand: SIGMA

≥99% (TLC), powder, endogenous histamine receptor agonist

동의어(들):

2-(4-Imidazolyl)ethylamine dihydrochloride

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크기 선택

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):

C₅H₉N₃ · 2HCl

CAS 번호:

56-92-8

Molecular Weight:

184.07

NACRES:

NA.77

PubChem Substance ID:

24277777

eCl@ss:

32160406

UNSPSC Code:

12352116

EC Number:

200-298-4

MDL number:

MFCD00012703

Beilstein/REAXYS Number:

3624116

Assay:

≥99% (TLC)

Form:

powder

Quality level:

200

주요 문서

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제품 이름

Histamine dihydrochloride, ≥99% (TLC), powder

InChI

1S/C5H9N3.2ClH/c6-2-1-5-3-7-4-8-5;;/h3-4H,1-2,6H2,(H,7,8);2*1H

InChI key

PPZMYIBUHIPZOS-UHFFFAOYSA-N

SMILES string

Cl[H].Cl[H].NCCc1c[nH]cn1

assay

≥99% (TLC)

form

powder

color

white to off-white

mp

249-252 °C (lit.)

storage temp.

2-8°C

Quality Level

200

Gene Information

human ... HRH1(3269), HRH2(3274)

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Application

Histamine dihydrochloride has been used:

as a orthograde cotransmitter in producing excitatory postsynaptic potential (EPSP)
to determine its level in fish using HPLC (high performance liquid chromatography)
to assess the tracheal response to antigens in guinea-pigs

Biochem/physiol Actions

Endogenous H₁ and H₂ histamine receptor agonist; activates nitric oxide synthetase; potent vasodilator.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

General description

Histamine dihydrochloride is a derivative of histamine. It prevents the formation of ROS (reactive oxygen species), which inhibits the activation of T cells and natural killer cells. Histamine dihydrochloride is implicated in tumor cell apoptosis. It prevents the relapse of acute myeloid leukemia in patients.