I2760
(−)-Isoproterenol (+)-bitartrate salt
β-adrenoceptor agonist, powder
동의어(들):
(−)-Isoprenaline (+)-bitartrate salt
조직 및 계약 가격을 보려면 로그인를 클릭합니다.
크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C11H17NO3 · C4H6O6
CAS 번호:
Molecular Weight:
361.34
UNSPSC Code:
51111800
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Form:
powder
Quality level:
제품 이름
(−)-Isoproterenol (+)-bitartrate salt, powder
SMILES string
O[C@@H]([C@H](O)C(O)=O)C(O)=O.CC(C)NC[C@H](O)c1ccc(O)c(O)c1
InChI
1S/C11H17NO3.C4H6O6/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;5-1(3(7)8)2(6)4(9)10/h3-5,7,11-15H,6H2,1-2H3;1-2,5-6H,(H,7,8)(H,9,10)/t11-;1-,2-/m00/s1
InChI key
LBOPECYONBDFEM-RWALOXMOSA-N
form
powder
color
white to off-white
solubility
H2O: ≥50 mg/mL, clear, colorless to faintly yellow
originator
Sanofi Aventis
Quality Level
Gene Information
human ... ADRB1(153), ADRB2(154), ADRB3(155)
관련 카테고리
Application
(−)-Isoproterenol (+)-bitartrate salt has been used:
- as a component in KRH medium for cyclic adenosine monophosphate (cAMP) assay
- to stimulate preadipocytes to study its concentration responsive curve
- to intraperitoneally administer to mice to evaluate whether the multi-dry-electrode plate (MDEP)-sensor system can assess drug responses
Biochem/physiol Actions
β-Adrenoceptor agonist; increases cytosolic cAMP.
Isoproterenol functions as an ovine pulmonary vein dilator.
Features and Benefits
This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
저장 등급
11 - Combustible Solids
wgk
WGK 3
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Adipocyte lipolysis and its adrenergic control were studied in vitro from normal patients and those with trauma and sepsis. The adrenergic receptors were studied in terms of their responsiveness, a measure of the postreceptor mechanism, and their sensitivity, a measure
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Nasal polyps and turbinates were obtained from individuals undergoing surgery for symptomatic nasal obstruction caused by nonatopic rhinosinusitis or allergic rhinosinusitis. One part of the tissue from each patient was fixed in neutral buffered formalin and prepared for study by
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Long-term potentiation (LTP) is activity-dependent enhancement of synaptic strength that can critically regulate long-term memory storage. Like memory, LTP exhibits at least two mechanistically distinct temporal phases. Early LTP (E-LTP) does not require protein synthesis, whereas the late phase of
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Local, externally applied pharmacological agents which are assumed to raise the c-AMP level, decrease the low pressure indentation value of the forehead skin of certain human volunteers.
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It was established in experiments on unanesthetized rats given intraventricular injections of drugs that hyperthermic effect of prostaglandin E2 (PGE2) was markedly weakened by administering clofelin while isoproterenol had no appreciable effect on PGE2 effects were not prevented by noradrenaline
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