K1757
Keratinocyte Growth Factor human
≥95% (SDS-PAGE and HPLC), recombinant, expressed in E. coli, powder, suitable for cell culture
동의어(들):
hFGF-7, hKGF, FGF-7, KGF
조직 및 계약 가격을 보려면 로그인를 클릭합니다.
크기 선택
제품정보 (DICE 배송 시 비용 별도)
Biological source:
human
Recombinant:
expressed in E. coli
Assay:
≥95% (SDS-PAGE and HPLC)
Form:
powder
Mol wt:
18.9 kDa
Impurities:
1 EU/μg
제품 이름
Keratinocyte Growth Factor human, KGF, recombinant, expressed in E. coli, powder, suitable for cell culture
biological source
human
recombinant
expressed in E. coli
assay
≥95% (SDS-PAGE and HPLC)
form
powder
potency
0.1-15 ng/mL ED50/EC50
quality
endotoxin tested
mol wt
18.9 kDa
packaging
pkg of 10 and 50 μg
technique(s)
cell culture | mammalian: suitable
impurities
1 EU/μg
UniProt accession no.
storage temp.
−20°C
Quality Level
Gene Information
human ... FGF7(2252)
유사한 제품을 찾으십니까? 방문 제품 비교 안내
General description
Keratinocyte Growth Factor(KGF) is a 18.9 kDa growth factor, spanning 163 amino acids, belongs to the fibroblast growth factor family. It includes a secretory signal sequence and shares 39% identity with FGF-Basic. It is expressed in a number of stromal fibroblast cell lines, mesenchymal cells but absent from normal glial cells and epithelial cell lines.
Application
Keratinocyte Growth Factor human has been used:
- as a component of epithelial growth medium
- as a positive control for antigen to determine the activity of the antibody
- to analyze the influence of KGF associated with thermo-sterilized carboxymethyl chitosan (NOCCts) in the reduction of pericardial adhesions
Biochem/physiol Actions
Keratinocyte Growth Factor(KGF) stimulates proliferation and differentiation of keratinocytes and other cells in the epithelium. It induces chemotaxis of microvascular endothelial cells and neovascularization of rat cornea. It stimulates the hyaluronic acid synthesis in proliferating and migrating basal cells. KGF contributes to the survival of cells under stress conditions. KGF is highly expressed in injured and inflamed epithelial cells, thereby, promotes wound healing.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.5 mg bovine serum albumin.
Analysis Note
Determined by a cell proliferation assay using 4MBr-5 cells.
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Synergism between keratinocyte growth factor and carboxymethyl chitosan reduces pericardial adhesions
Lopes JB, et al.
The Annals of Thoracic Surgery, 90(2), 566-572 (2010)
Stimulation of in vivo angiogenesis by in situ crosslinked, dual growth factor-loaded, glycosaminoglycan hydrogels
Elia R, et al.
Biomaterials, 31(17), 4630-4638 (2010)
Characteristics of MIC-1 antlerogenic stem cells and their effect on hair growth in rabbits.
Cegielski M, et al.
In Vivo, 27(1), 97-106 (2013)
Keratinocyte growth factor stimulates migration and hyaluronan synthesis in the epidermis by activation of keratinocyte hyaluronan synthases 2 and 3
Karvinen S, et al.
The Journal of biological chemistry, 278(49), 49495-49504 (2003)
Nrf2 transcription factor, a novel target of keratinocyte growth factor action which regulates gene expression and inflammation in the healing skin wound
Braun S, et al.
Molecular and Cellular Biology, 22(15), 5492-5505 (2002)
관련 콘텐츠
Datasheet
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.