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Merck

L7895

Lipopolysaccharides from Salmonella typhosa

γ-irradiated, BioXtra, suitable for cell culture

동의어(들):

LPS

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제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12352201
NACRES:
NA.75
MDL number:
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제품 이름

Lipopolysaccharides from Salmonella typhosa, γ-irradiated, BioXtra, suitable for cell culture

biological source

bacterial (Salmonella typhosa)

sterility

γ-irradiated

product line

BioXtra

form

lyophilized powder

purified by

gel-filtration chromatography

technique(s)

cell culture | mammalian: suitable

impurities

<1% Protein (Lowry)

color

white to faint yellow

solubility

water: 0.90-1.10 mg/mL, faintly hazy to hazy, colorless to faintly yellow

storage temp.

2-8°C

Quality Level

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Application

Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4), a member of the Toll-like receptor protein family, which recognizes common pathogen-associated molecular-patterns (PAMPs).
Lipopolysaccharides from Salmonella typhosa are used in cell culture and cell binding applications. The role of LPS in the secretion of TNF-α and IL-6 was studied in mouse spleen cell culture. It was used to study the role of inflammatory responses in multiple sclerosis.

Biochem/physiol Actions

Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4), a member of the Toll-like receptor protein family, which recognizes common pathogen-associated molecular-patterns (PAMPs).

Other Notes

To gain a comprehensive understanding of our extensive range of Lipopolysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

저장 등급

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Yasuhisa Ano et al.
Scientific reports, 10(1), 20028-20028 (2020-11-20)
The prevention of age-related cognitive decline and dementia is becoming a high priority because of the rapid growth of aging populations. We have previously shown that hop bitter acids such as iso-α-acids (IAAs) and matured hop bitter acids (MHBAs) activate
Aurélien Godinat et al.
Current protocols in chemical biology, 6(3), 169-189 (2014-09-11)
The great complexity of many human pathologies, such as cancer, diabetes, and neurodegenerative diseases, requires new tools for studies of biological processes on the whole organism level. The discovery of novel biocompatible reactions has tremendously advanced our understanding of basic
D N Dao et al.
Infection and immunity, 72(4), 2067-2074 (2004-03-25)
The mycobacterial cell wall component lipoarabinomannan (LAM) has been described as a virulence factor of Mycobacterium tuberculosis, and modification of the terminal arabinan residues of this compound with mannose caps (producing mannosyl-capped LAM [ManLAM]) in M. tuberculosis or with phosphoinositol
Yasuhisa Ano et al.
Nutrients, 11(9) (2019-09-12)
The number of patients with mental illnesses is rapidly increasing, and daily lifestyle is closely associated with the development of symptoms. It is suggested that inflammatory molecules derived from microglia play crucial roles for the pathophysiology of depression. In the
Armin Neininger et al.
The Journal of biological chemistry, 277(5), 3065-3068 (2001-12-14)
We demonstrate that lipopolysaccharide-induced tumor necrosis factor (TNF) biosynthesis becomes independent of MAPKAP kinase 2 (MK2) when the AU-rich element (ARE) of the TNF gene is deleted. In spleen cells and macrophages where TNF biosynthesis is restored as a result

문서

Explore the structure, function, and diverse applications of Lipopolysaccharides. Discover their role in bacteria, serological specificity, and research potential.

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