L8000
L-Leucine
≥98% (HPLC), suitable for ligand binding assays
동의어(들):
(S)-2-Amino-4-methylpentanoic acid
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
(CH3)2CHCH2CH(NH2)CO2H
CAS 번호:
Molecular Weight:
131.17
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-522-0
MDL number:
Beilstein/REAXYS Number:
1721722
제품 이름
L-Leucine, reagent grade, ≥98% (HPLC)
InChI key
ROHFNLRQFUQHCH-YFKPBYRVSA-N
InChI
1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1
SMILES string
CC(C)C[C@H](N)C(O)=O
grade
reagent grade
assay
≥98% (HPLC)
form
powder
technique(s)
ligand binding assay: suitable
impurities
isoleucine and methionine, essentially free
color
white to off-white
mp
>300 °C (lit.)
application(s)
peptide synthesis
Quality Level
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Application
L-Leucine has been used as an agonist of mechanistic target of rapamycin (mTOR) to determine whether AMPK/mTOR pathway is involved in berberine-mediated autophagy in J774A.1 cells. It has also been used for the selection of transformed cells.
Biochem/physiol Actions
Leucine is a non-glucogenic, essential amino acid. It is a branched-chain amino acid that is a structural component of proteins. Leucine positively influences insulin release to eliminate toxic sugars out of the blood. The degradation of leucine leads to the formation of ketone bodies.
저장 등급
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
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Bio-protocol (2017)
Dr. Victor Prisk
The Leucine Factor Diet: The Scientifically-Proven Approach to Combat Sugar, Burn Fat and Build Muscle (2015)
Berberine alleviates ox-LDL induced inflammatory factors by up-regulation of autophagy via AMPK/mTOR signaling pathway
Xiaodi Fan
Journal of Translational Medicine (2015)
Sergio R Santa Maria et al.
Astrobiology (2020-01-07)
The biological risks of the deep space environment must be elucidated to enable a new era of human exploration and scientific discovery beyond low earth orbit (LEO). There is a paucity of deep space biological missions that will inform us
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