L9150
N-Lauroylsarcosine sodium salt
detergent for use in cell lysis
동의어(들):
Sodium lauroyl sarcosinate, N-Dodecanoyl-N-methylglycine sodium salt, Sarkosyl NL
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
CH3(CH2)10CON(CH3)CH2COONa
CAS 번호:
Molecular Weight:
293.38
UNSPSC Code:
12161902
NACRES:
NA.52
PubChem Substance ID:
EC Number:
205-281-5
Beilstein/REAXYS Number:
5322974
MDL number:
InChI key
KSAVQLQVUXSOCR-UHFFFAOYSA-M
InChI
1S/C15H29NO3.Na/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19;/h3-13H2,1-2H3,(H,18,19);/q;+1/p-1
SMILES string
[Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O
grade
Molecular Biology
description
anionic
product line
BioReagent
assay
≥94%
form
powder
mol wt
micellar avg mol wt 600
aggregation number
2
technique(s)
protein purification: suitable, protein quantification: suitable
CMC
14.6 mM (20-25°C)
solubility
H2O: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow
foreign activity
DNase, RNase, none detected
storage temp.
room temp
Quality Level
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General description
Sodium lauroyl sarcosinate, the sodium salt of an acyl derivative of sarcosine—a natural amino acid occurring in muscles and body tissues—stands out as a valuable component in molecular biology, biochemical, and cell biology research. Derived from a natural fatty acid and the amino acid derivative sarcosine, N-Lauroylsarcosine is a biodegradable anionic surfactant usually synthesized through acylation and neutralization reactions involving lauric acid and sodium sarcosine.
This amino acid-type anionic surfactant, also recognized as a fatty acid amide and detergent, exhibits protein denaturant potency and has been integrated into lysing solutions, such as the cornet assay. Its application extends to lysing protoplasts for chromosomal DNA isolation from Streptococcus mutans. Notably, Lauroylsarcosine Sodium Salt, characterized by its ionic detergent properties, is commonly employed for purifying membrane proteins. Additionally, Sodium Lauroyl Sarcosine also plays a crucial role in concentrated salt solutions, facilitating cell lysis in RNA purification protocols and membrane solubilization. Whether it′s breaking down cell structures or facilitating membrane protein purification, this mild surfactant proves valuable in various applications within the realms of biology and biochemistry.
This amino acid-type anionic surfactant, also recognized as a fatty acid amide and detergent, exhibits protein denaturant potency and has been integrated into lysing solutions, such as the cornet assay. Its application extends to lysing protoplasts for chromosomal DNA isolation from Streptococcus mutans. Notably, Lauroylsarcosine Sodium Salt, characterized by its ionic detergent properties, is commonly employed for purifying membrane proteins. Additionally, Sodium Lauroyl Sarcosine also plays a crucial role in concentrated salt solutions, facilitating cell lysis in RNA purification protocols and membrane solubilization. Whether it′s breaking down cell structures or facilitating membrane protein purification, this mild surfactant proves valuable in various applications within the realms of biology and biochemistry.
Application
Suitable for
- solubilization and separation of membrane proteins
- lysis of cells during the isolation of RNA
- inhibition of hexokinase
Features and Benefits
- Suitable for Molecular Biology, Biochemical and Cell Biology research
- Can be used for Protein Purification and Quantification
- High purity product for research applications
Other Notes
Anionic surfactant.
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Inhalation - Eye Dam. 1 - Skin Irrit. 2
저장 등급
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 1
flash_point_f
512.6 °F - closed cup
flash_point_c
267 °C - closed cup
ppe
Eyeshields, Gloves, type N95 (US)
M Swenshon et al.
Journal of clinical microbiology, 36(7), 1902-1906 (1998-07-03)
The present study was designed to identify and comparatively investigate 35 beta-hemolytic streptococci isolated from stranded harbor porpoises or from animals caught in fishing nets of the North and Baltic seas. According to biochemical and serological data and to lectin
A R Günthert et al.
The Journal of cell biology, 134(4), 1089-1096 (1996-08-01)
Ligation of CD95 (APO-1/Fas) cell surface receptors induces death in apoptosis-sensitive cells. Induction of apoptosis in adherent gamma interferon-stimulated HT-29 and COLO 205 colon carcinoma cells by cross-linking CD95 with anti-APO-1 monoclonal antibody resulted in detachment of the cells from
Rhonda I Hobb et al.
Microbiology (Reading, England), 155(Pt 3), 979-988 (2009-02-28)
Although infection with Campylobacter jejuni is one of the leading causes of gastroenteritis worldwide, relatively little is known about the factors that are required to elicit a protective immune response. The need for a vaccine against this pathogen is well
Joanna A Korecka et al.
PloS one, 8(5), e63862-e63862 (2013-06-01)
Multiple genetic and environmental factors play a role in the development and progression of Parkinson's disease (PD). The main neuropathological hallmark of PD is the degeneration of dopaminergic (DAergic) neurons in the substantia nigra pars compacta. To study genetic and
Nadine Schrode et al.
Nature genetics, 51(10), 1475-1485 (2019-09-25)
The mechanisms by which common risk variants of small effect interact to contribute to complex genetic disorders are unclear. Here, we apply a genetic approach, using isogenic human induced pluripotent stem cells, to evaluate the effects of schizophrenia (SZ)-associated common
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