M0252

Methylglyoxal solution

Name: Methylglyoxal solution
Brand: SIGMA

~40% in H₂O

동의어(들):

Acetylformaldehyde, Pyruvaldehyde, Pyruvic aldehyde

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크기 선택

제품정보 (DICE 배송 시 비용 별도)

Linear Formula:

CH₃COCHO

CAS 번호:

78-98-8

Molecular Weight:

72.06

UNSPSC Code:

12352204

NACRES:

NA.32

PubChem Substance ID:

24896540

MDL number:

MFCD00006960

Beilstein/REAXYS Number:

906750

주요 문서

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기술 서비스

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도움 문의

기술 서비스

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도움 문의

InChI

1S/C3H4O2/c1-3(5)2-4/h2H,1H3

SMILES string

[H]C(=O)C(C)=O

InChI key

AIJULSRZWUXGPQ-UHFFFAOYSA-N

form

liquid

concentration

~40% (enzymatic), ~40% in H₂O

density

1.17 g/mL at 25 °C (lit.)

storage temp.

2-8°C

Quality Level

200

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General description

Methylglyoxal (MG) is a glucose metabolite, which is linked to peripheral neuropathy and pain in diabetic patients. It enhances intracellular calcium in sensory neurons and produces behavioral nociception. Methylglyoxal has antibacterial property. MG functions as a protein-glycating agent and precursor of advanced glycation end products. It impairs diabetic wound healing.

Application

Methylglyoxal solution has been used:

to assess glyoxalase 1 (GLO1) enzymatic activity
as an advanced glycation end (AGE) forming agent for the preparation of albumin in vitro
to regulate anxiety like behavior in mice
to induce peritoneal fibrosis in rats
to study the chromatographic retention characteristics of organic chemicals and metal DNA adducts
for intraplantar injection in mice to investigate peripheral and central components of methylglyoxal (MG)-transient receptor potential ankyrin 1 (TRPA1)-adenylyl cyclase 1 isoform (AC1) pathway

pictograms

GHS08,GHS05,GHS07

signalword

Danger

hcodes

H290,H317,H318,H341

pcodes

P202 - P234 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313

Hazard Classifications

Eye Dam. 1 - Met. Corr. 1 - Muta. 2 - Skin Sens. 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

저장 등급

10 - Combustible liquids

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시험 성적서(COA)

Lot/Batch Number

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COA 검색

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Measurement of the modification and interference rate of urinary albumin detected by size-exclusion HPLC

Marko L, et al.

Physiological Measurement, 30(10), 1137-1137 (2009)

Methylglyoxal?a potential risk factor of manuka honey in healing of diabetic ulcers

Majtan J

Evidence-Based Complementary and Alternative Medicine : ECAM, 2011 (2011)

Neuronal overexpression of Glo1 or amygdalar microinjection of methylglyoxal is sufficient to regulate anxiety-like behavior in mice

McMurray KMJ, et al.

Behavioural Brain Research, 301, 119-123 (2016)

The Therapeutic Potential of Human Umbilical Mesenchymal Stem Cells From Wharton's Jelly in the Treatment of Rat Peritoneal Dialysis-Induced Fibrosis

Fan YP, et al.

Stem Cells Translational Medicine, 5(2), 235-247 (2016)

Methylglyoxal requires AC1 and TRPA1 to produce pain and spinal neuron activation

Griggs RB, et al.

Frontiers in Neuroscience, 11, 679-679 (2017)

모든 관련된 서류 보기

문서

Quantification of Methylglyoxal in Manuka Honey - A Simple HPTLC Based Approach

High-Performance Thin-Layer chromatography (HPTLC) quantification of methylglyoxal (MGO) in complex and matrix rich manuka honey offering quick sample preparation, high-matrix tolerance, and high-throughput.

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

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Methylglyoxal solution