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Merck

M2172

1-Thioglycerol

BioXtra, ≥97%

동의어(들):

α-Monothioglycerol, α-Thioglycerol, 3-Mercapto-1,2-propanediol

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
HSCH2CH(OH)CH2OH
CAS 번호:
96-27-5
Molecular Weight:
108.16
UNSPSC Code:
12352211
NACRES:
NA.25
PubChem Substance ID:
24896709
EC Number:
202-495-0
Beilstein/REAXYS Number:
1732046
MDL number:
MFCD00004879

주요 문서

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InChI key

PJUIMOJAAPLTRJ-UHFFFAOYSA-N

InChI

1S/C3H8O2S/c4-1-3(5)2-6/h3-6H,1-2H2

SMILES string

OCC(O)CS

product line

BioXtra

assay

≥97%

form

liquid

impurities

≤0.0005% Phosphorus (P)

ign. residue

≤0.1%

Quality Level

200

bp

118 °C/5 mmHg (lit.)

density

1.25 g/mL at 25 °C (lit.)

cation traces

Al: ≤0.0005%, Ca: ≤0.0005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Mg: ≤0.0005%, NH4+: ≤0.05%, Na: ≤0.02%, Pb: ≤0.001%, Zn: ≤0.0005%

storage temp.

2-8°C

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관련 카테고리

General description

1-Thioglycerol stimulates the synthesis of porphyrin in aerobically growing Escherichia coli. It is an inhibitor of glycerol kinase activity in vitro and in situ.

Application

It has been used in a study to assess thiol-sensitive genes and promoters of Escherichia coli.

Preparation Note

This product is miscible in ethanol (1 ml/ml, 50%, v/v), yielding a clear, colorless solution. It is also miscible in water (0.1 M).

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Skin Irrit. 2 - Skin Sens. 1B

저장 등급

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

210.2 °F - closed cup

flash_point_c

99 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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시험 성적서(COA)

Lot/Batch Number
0000498752
0000498753
0000498752
0000478699
0000478699

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문서 라이브러리 방문

W K Seltzer et al.
Life sciences, 39(16), 1417-1424 (1986-10-20)
The infantile form of glycerol kinase (GK) deficiency (McKusick No. 30703) (1) is characterized by adrenal cortical insufficiency, adrenal hypoplasia and developmental delay. The underlying biochemical mechanism(s) responsible for the observed clinical presentations are undetermined. Pursuant to our examination of
G T Javor
Journal of bacteriology, 171(10), 5607-5613 (1989-10-01)
The effect of 1-thioglycerol on the expression of genes of Escherichia coli was investigated. Pulse-labeled proteins from aerobically growing, 1-thioglycerol-treated E. coli were separated by two-dimensional gel electrophoresis, and their radioactivities were compared with those of identical proteins from nontreated
G T Javor et al.
Journal of bacteriology, 170(7), 3291-3293 (1988-07-01)
Mu dX(lac) insertion mutants of Escherichia coli CSH50 in which the expression of the lacZ gene was sensitive to the presence of exogenous 1-thioglycerol or dithiothreitol were isolated. Both stimulatory and inhibitory mutants were found. The existence of several thiol-sensitive
C Unni et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 71(4), 1402-1407 (2008-06-11)
Nanoparticles of CdS were prepared at 303 K by aqueous precipitation method using CdSO4 and (NH4)2S in presence of the stabilizing agent thioglycerol. Adjustment of the thioglycerol (T) to ammonium sulphide (A) ratio (T:A) from 1:25 to 1:3.3 was done
L Tang et al.
Journal of biomedical materials research, 41(2), 333-340 (1998-06-25)
Biomaterial-mediated complement activation repeatedly has been invoked as a trigger of phagocyte reactions and inflammation. However, a direct correlation between complement activation and inflammatory responses to biomaterial surfaces has yet to be established. Using an animal implantation model and gold
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