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Merck

N144

Nitrendipine

>95%, powder

동의어(들):

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl methyl ester

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C18H20N2O6
CAS 번호:
Molecular Weight:
360.36
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
254-513-1
MDL number:
Assay:
>95%
Form:
powder
Quality level:
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Quality Level

assay

>95%

form

powder

color

yellow to green

solubility

methanol: 15 mg/mL, DMSO: 17.5 mg/mL, H2O: insoluble

SMILES string

CCOC(=O)C1=C(C)NC(C)=C(C1c2cccc(c2)[N+]([O-])=O)C(=O)OC

InChI

1S/C18H20N2O6/c1-5-26-18(22)15-11(3)19-10(2)14(17(21)25-4)16(15)12-7-6-8-13(9-12)20(23)24/h6-9,16,19H,5H2,1-4H3

InChI key

PVHUJELLJLJGLN-UHFFFAOYSA-N

Biochem/physiol Actions

Ca2+ channel blocker; anti-hypertensive.


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문서 라이브러리 방문



Xi Zhang et al.
International journal of pharmaceutics, 431(1-2), 45-52 (2012-05-01)
A novel active and multi-dose dry powder inhaler (DPI) was developed and evaluated to deliver a small quantity (100-500 μg) of pure drug without any excipient. This dry powder inhaler utilized two compressed air flows to dispense and deliver drug
Dengning Xia et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 46(5), 446-454 (2012-04-10)
The amorphous-to-crystalline transformation of nitrendipine was investigated using Raman spectroscopy and X-ray powder diffraction (XRPD). The nucleation and growth rate of crystalline nitrendipine in a medium containing poly (vinyl alcohol) (PVA) and polyethylene glycol (PEG 200) were quantitatively determined using
Annik Bergeron et al.
Bioanalysis, 4(8), 897-908 (2012-04-27)
In the past several years, the impact of changing counter ions while keeping the same anticoagulant in bioanalytical LC-MS/MS methods has become a highly discussed topic. In order to confirm that there is no impact from counter ions, matrix effect