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Merck

N2765

4-Nitrophenyl phosphate disodium salt hexahydrate

chromogenic, tablet

동의어(들):

p-Nitrophenyl phosphate disodium hexahydrate, Disodium 4-nitrophenyl phosphate hexahydrate, di-Sodium 4-nitrophenyl phosphate, pNPP disodium hexahydrate

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
O2NC6H4OP(O)(ONa)2 · 6H2O
CAS 번호:
333338-18-4
Molecular Weight:
371.14
NACRES:
NA.83
PubChem Substance ID:
24897592
UNSPSC Code:
12352204
EC Number:
224-246-5
MDL number:
MFCD00066288
Beilstein/REAXYS Number:
5324661

주요 문서

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제품 이름

4-Nitrophenyl phosphate disodium salt hexahydrate, tablet

InChI key

KAKKHKRHCKCAGH-UHFFFAOYSA-L

InChI

1S/C6H6NO6P.2Na.6H2O/c8-7(9)5-1-3-6(4-2-5)13-14(10,11)12;;;;;;;;/h1-4H,(H2,10,11,12);;;6*1H2/q;2*+1;;;;;;/p-2

SMILES string

O.O.O.O.O.O.[Na+].[Na+].[O-][N+](=O)c1ccc(OP([O-])([O-])=O)cc1

form

tablet

solubility

water, high purity: 0.25 tablet/mL, clear, colorless

storage temp.

−20°C

Quality Level

300

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관련 카테고리

General description

Chromogenic substrate for the determination of acid and alkaline phosphatases. The reaction produces a soluble end product that is yellow in color. The reaction may be stopped with 3 N NaOH and read at 405 nm.

Application

4-Nitrophenyl phosphate disodium salt hexahydrate has been used:
  • as a substrate for alkaline phosphatase coupled anti-rabbit antibody in enzyme-linked immunosorbent assay (ELISA)
  • as a substrate for the mouse secondary antibody linked to alkaline phosphatase in immunoenzymometric assay
  • in ELISA to analyze the presence of antibodies to Pseudomonas aeruginosa in animal serum sample

Preparation Note

Contains 20 mg substrate per tablet

저장 등급

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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시험 성적서(COA)

Lot/Batch Number
0000486044
0000512549
0000496018
0000496018
0000512549

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문서 라이브러리 방문

Amanda L Miller et al.
PLoS pathogens, 16(7), e1008591-e1008591 (2020-07-10)
Reactive arthritis, an autoimmune disorder, occurs following gastrointestinal infection with invasive enteric pathogens, such as Salmonella enterica. Curli, an extracellular, bacterial amyloid with cross beta-sheet structure can trigger inflammatory responses by stimulating pattern recognition receptors. Here we show that S.
Marcus J Hines et al.
Cell reports, 33(9), 108436-108436 (2020-12-03)
The phosphatidylinositol 3-kinase (PI3K) signaling cascade downstream of the B cell receptor (BCR) signalosome is essential for B cell maturation. Proper signaling strength is maintained through the PI3K negative regulator phosphatase and tensin homolog (PTEN). Although a role for microRNA
Mihaela Gadjeva et al.
Journal of immunology (Baltimore, Md. : 1950), 184(1), 296-302 (2009-12-02)
The inflammatory response to Pseudomonas aeruginosa is not properly regulated in the lungs of patients with cystic fibrosis (CF). In the lung epithelium of individuals with wild-type CF transmembrane conductance regulator, lipid rafts containing CF transmembrane conductance regulator are rapidly
Christina Papista et al.
Kidney international, 88(2), 276-285 (2015-03-26)
IgA1 complexes containing deglycosylated IgA1, IgG autoantibodies, and a soluble form of the IgA receptor (sCD89), are hallmarks of IgA nephropathy (IgAN). Food antigens, notably gluten, are associated with increased mucosal response and IgAN onset, but their implication in the
Masaya Yokota et al.
Arthritis research & therapy, 16(2), R72-R72 (2014-03-19)
In addition to the pivotal roles of mast cells in allergic diseases, recent data suggest that mast cells play crucial roles in a variety of autoimmune responses. However, their roles in the pathogenesis of autoimmune skeletal muscle diseases have not
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