N3398
S-Nitroso-N-acetyl-DL-penicillamine
≥97%, Nitric oxide donor, powder
동의어(들):
N-Acetyl-3-(nitrosothio)-DL-valine, S-Nitroso-N-acetylpenicillamine, SNAP
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C7H12N2O4S
CAS 번호:
Molecular Weight:
220.25
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.32
MDL number:
제품 이름
S-Nitroso-N-acetyl-DL-penicillamine, ≥97%, powder
SMILES string
CC(=O)NC(C(O)=O)C(C)(C)SN=O
InChI
1S/C7H12N2O4S/c1-4(10)8-5(6(11)12)7(2,3)14-9-13/h5H,1-3H3,(H,8,10)(H,11,12)
InChI key
ZIIQCSMRQKCOCT-UHFFFAOYSA-N
assay
≥97%
form
powder
color
faint green to very dark green
solubility
H2O: ≥2 mg/mL, DMSO: ≥20 mg/mL, clear (faint green to very dark green)
storage temp.
−20°C
Quality Level
관련 카테고리
Application
S-Nitroso-N-acetyl-DL-penicillamine (SNAP) has been used:
- as a positive control in nitrite generation assay.
- to block the activity of endogenous transglutaminase (TG2).
- in proliferation assays to generate nitric oxide (NO) in cell cultures.
Biochem/physiol Actions
NO donor; vasodilator, smooth muscle relaxant, lymphocyte activator. Activates soluble guanylyl cyclase.
SNAP, a nitrosothiol derivative, releases nitric oxide (NO.) under physiological conditions thus making it a useful tool for studying pharmacological and physiological actions of NO. Because of its NO releasing properties SNAP is a potent vasodilator in vitro and in vivo and is less prone to produce pharmacological tolerance.
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Muta. 2 - Skin Irrit. 2
Immunomodulatory activities of chitin microparticles on Leishmania major-infected murine macrophages.
Dehghani F
Archives of Medical Research, 42(7), 572-576 (2011)
Sophiya Garasia et al.
Scientific reports, 7(1), 1629-1629 (2017-05-11)
We assessed the association between depression status and prevalent and incident type 2 diabetes (T2D) as well as the interaction between depression and a genetic risk score (GS) based on 20 T2D single-nucleotide polymorphisms (SNPs) in a multi-ethnic longitudinal study.
Jodie D Anderson et al.
Journal of veterinary internal medicine, 33(4), 1593-1601 (2019-05-28)
Intravenous continuous rate infusion (IVCRI) of lispro at a starting dose of 0.09 U/kg/h and the use of 0.9% sodium chloride (NaCl) for fluid resuscitation in cats with diabetic ketoacidosis (DKA) have not been reported. Protocols for correction of electrolyte deficiencies
Lethal autoimmune myocarditis in interferon-gamma receptor-deficient mice: enhanced disease severity by impaired inducible nitric oxide synthase induction.
Eriksson U
Circulation, 103(1), 18-21 (2001)
The redox state of transglutaminase 2 controls arterial remodeling.
van den Akker J
PLoS ONE, 6(8), e23067-e23067 (2011)
문서
Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.
관련 콘텐츠
Information
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