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Merck

N7660

4-Nitrophenol

chromogenic, liquid

동의어(들):

p-Nitrophenol solution

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C6H5NO3
CAS 번호:
Molecular Weight:
139.11
UNSPSC Code:
12352204
eCl@ss:
39032018
PubChem Substance ID:
NACRES:
NA.28
MDL number:
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제품 이름

4-Nitrophenol solution, 10 mM

SMILES string

Oc1ccc(cc1)[N+]([O-])=O

InChI

1S/C6H5NO3/c8-6-3-1-5(2-4-6)7(9)10/h1-4,8H

InChI key

BTJIUGUIPKRLHP-UHFFFAOYSA-N

form

liquid

concentration

10 mM

storage temp.

2-8°C

Quality Level

Gene Information

human ... UGT1A4(54657)

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General description

4-Nitrophenol is a phenolic compound present as a chemical intermediate and breakdown product during the production of organophosphorus insecticide derivatives of parathion. It is an intermediate during the synthesis of paracetamol. 4-Nitrophenol is a chromogenic catalytic by product of the synthetic substrate 4-nitrophenyl phosphate. It is majorly used as a reference standard in alkaline phosphatase assay. 4-Nitrophenol is nonbiodegradable and its derivatives are used for herbicide and fungicide production.

Application

4-Nitrophenol solution has been used:
  • in the generation of standard curve for quantifying alkaline phosphatase activity of mesenchymal stem cells
  • bone marrow stromal cells (BMSCs)
  • for quantifying β-hexosaminidase activity in HeLa cells
  • as a standard for calorimetric determination of alkaline phosphatase activity at 405 nm
  • for assessing the β-hexosamindase activity

Preparation Note

Prepared as a 1.39 mg/ml solution suitable for use as a calibrator in alkaline phosphatase assays (such as Bessey-Lowry-Brock method) using p-nitrophenol phosphate as a substrate.

저장 등급

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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문서 라이브러리 방문

Degradation of p-nitrophenol in aqueous solution by microwave assisted oxidation process through a granular activated carbon fixed bed
Bo L, et al.
Water Research, 40(16), 3061-3068 (2006)
Biphasic regulation of lysosomal exocytosis by oxidative stress
Ravi S, et al.
Cell Calcium, 60(5), 356-362 (2016)
Competitive flow immunoassay with fluorescence detection for determination of 4-nitrophenol.
<BIG>Nistor, C., Oubina, A., Marco, M. P., Barcelo, D., &amp; Emneus, J.</BIG>
Analytica Chimica Acta, 426, 185-195 (2001)
Prema B Rapuri et al.
The Journal of steroid biochemistry and molecular biology, 103(3-5), 368-371 (2007-01-16)
Of the various risk factors contributing to osteoporosis, dietary/lifestyle factors are important. In a clinical study we reported that women with caffeine intakes >300 mg/day had higher bone loss and women with vitamin D receptor (VDR) variant, tt were at
Porous Polylactic Acid-Silica Hybrids: Preparation, Characterization, and Study of Mesenchymal Stem Cell Osteogenic Differentiation
Pandis C, et al.
Macromolecular Bioscience, 15(2), 262-274 (2015)

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