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크기 선택
제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
CH3CO2C6H4NO2
CAS 번호:
Molecular Weight:
181.15
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
212-593-5
MDL number:
Beilstein/REAXYS Number:
515874
제품 이름
4-Nitrophenyl acetate, esterase substrate
InChI key
QAUUDNIGJSLPSX-UHFFFAOYSA-N
InChI
1S/C8H7NO4/c1-6(10)13-8-4-2-7(3-5-8)9(11)12/h2-5H,1H3
SMILES string
CC(=O)Oc1ccc(cc1)[N+]([O-])=O
assay
≥98% (TLC)
form
powder or crystals
Quality Level
Gene Information
human ... PON1(5444)
storage temp.
−20°C
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General description
Chromogenic esterase substrate.
Application
4-Nitrophenyl acetate has been used:
- to evaluate esterase activity in human embryonic kidney cell line
- in carbonic anhydrase inhibition assay
- to study its conversion to p-nitrophenol (p-NP) by the esterase activity of bovine serum albumin
- as a substrate to determine carboxylesterase (CES) activity in mouse liver cells
- to study the advantages of bioconjugation of cross-linked enzyme aggregates (CLEAs) and magnetic iron oxide nanoparticles (MIONPs) in magnetic CLEAs matrix
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Ox. Sol. 3 - Skin Sens. 1
저장 등급
5.1B - Oxidizing hazardous materials
wgk
WGK 3
flash_point_f
No data available
flash_point_c
No data available
ppe
Eyeshields, Gloves, type N95 (US)
Novel Redox-Dependent Esterase Activity (EC 3.1.1.2) for DJ-1: Implications for Parkinson's Disease.
Emmanuel Vázquez-Mayorga et al.
International journal of molecular sciences, 17(8) (2016-08-25)
Mutations the in human DJ-1 (hDJ-1) gene are associated with early-onset autosomal recessive forms of Parkinson's disease (PD). hDJ-1/parkinsonism associated deglycase (PARK7) is a cytoprotective multi-functional protein that contains a conserved cysteine-protease domain. Given that cysteine-proteases can act on both
Michelle R Baker et al.
Biochemistry research international, 2011, 739712-739712 (2011-09-16)
Persistent alteration of protein conformation due to interaction with isoflurane may be a novel molecular aspect of preconditioning. We preincubated human serum albumin with isoflurane, dialyzed to release agent, and assessed protein conformation. Susceptibility to chemical modification by methylglyoxal and
Immunomodulatory, antiglycation and anti-ulcerative properties of Ruellia squarrosa Fenzl Acanthaceae
Afzal K, et al.
Tropical Journal of Pharmaceutical Research, 16(8), 1751-1755 (2017)
Beyond esterase-like activity of serum albumin. Histidine-(nitro) phenol radical formation in conversion cascade of p-nitrophenyl acetate and the role of infrared light
Kowacz M and Warszynski P
arXiv (2018)
Impact of diet on irinotecan toxicity in mice
Mallick P, et al.
Chemico-Biological Interactions, 291, 87-94 (2018)
관련 콘텐츠
Product Information Sheet
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