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Merck

N8410

β-Nicotinamide adenine dinucleotide

greener alternative

pkg of 20 mg (per vial)

동의어(들):

β-DPN, β-NAD, Coenzyme 1, Cozymase, DPN, Diphosphopyridine nucleotide, Nadide

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C21H27N7O14P2
CAS 번호:
53-84-9
Molecular Weight:
663.43
NACRES:
NA.51
PubChem Substance ID:
329818687
eCl@ss:
39200202
UNSPSC Code:
41106305
EC Number:
200-184-4
MDL number:
MFCD00036253
Beilstein/REAXYS Number:
3584133
Form:
powder

주요 문서

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InChI key

BAWFJGJZGIEFAR-NNYOXOHSSA-N

InChI

1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1

SMILES string

NC(=O)c1ccc[n+](c1)[C@@H]2O[C@H](COP([O-])(=O)OP(O)(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@@H](O)[C@H]2O

form

powder

packaging

pkg of 20 mg (per vial)

Quality Level

200

greener alternative product characteristics

Waste Prevention
Catalysis
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

greener alternative category

DfS-Developed

storage temp.

−20°C

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관련 카테고리

General description

We are committed to bringing you Greener Alternative Products that adhere to one or more of the 12 Principles of Green Chemistry. Beta-Nicotinamide adenine dinucleotide is a bio-derived redox cofactor that works together with enzymes as part of a biocatalyst system. It can be efficiently recycled in many reactions, enabling selective oxidations while reducing waste and supporting greener, more sustainable chemical processes. Click here for more information.

Application

β-Nicotinamide adenine dinucleotide (NAD+) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases).
β-Nicotinamide adenine dinucleotide has been used in the master mix for coupled enzyme assay to estimate pectin methylesterase activity.

Biochem/physiol Actions

β-Nicotinamide adenine dinucleotide (β-NADH) reduced form is an essential cofactor in all the living organisms. β-NADH functions as a hydride acceptors in biochemical redox reactions. It acts as a cell signaling molecule and is a potent neurotransmitter and neuromodulator in the peripheral nervous system. In brain, it mediates Ca2+ homeostasis, energy metabolism, aging and neuronal death.
Electron acceptor

Other Notes

Packaged based on NAD content as determined by UV-Vis.
This is the common form of NAD.

저장 등급

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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시험 성적서(COA)

Lot/Batch Number
0000258732
SLCR4410
SLCR4410
0000258732
SLCN2603

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문서 라이브러리 방문

The biosynthesis of nicotinamide adenine dinucleotides in bacteria
Begley TP, et al.
Vitamins and Hormones, 61, 103-119 (2001)
Irina Lazarova et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 83, 70-78 (2016-10-25)
The aim of this study was to investigate the effect of Asphodeline lutea (L.) Rchb. dry root extract (ALE) administered alone and against carbon tetrachloride (CCl4)-induced liver injury in vitro/in vivo. The dried roots of A. lutea were extracted with
Pectin Methylesterase Activity Assay for Plant Material
Mueller K, et al.
Plant Physiology, 3(17), e894-e894 (2013)
Pectin de-methylesterification and AGP increase promote cell wall remodeling and are required during somatic embryogenesis of Quercus suber
Perez-Perez Y, et al.
Frontiers in Plant Science, 9, e894-e894 (2018)
Release, neuronal effects and removal of extracellular beta-nicotinamide adenine dinucleotide beta-NAD+ in the rat brain
Durnin L, et al.
The European Journal of Neuroscience, 35(3), 423-435 (2012)
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