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크기 선택
제품정보 (DICE 배송 시 비용 별도)
Conjugate:
unconjugated
Clone:
132.38, monoclonal
Application:
immunocytochemistry
immunoprecipitation (IP)
indirect ELISA
microarray
western blot
immunoprecipitation (IP)
indirect ELISA
microarray
western blot
Species reactivity:
rat
Citations:
9
Technique(s):
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
indirect ELISA: suitable
microarray: suitable
western blot: 1 μg/mL using rat brain neonatal extract
immunoprecipitation (IP): suitable
indirect ELISA: suitable
microarray: suitable
western blot: 1 μg/mL using rat brain neonatal extract
Uniprot accession no.:
제품 이름
Monoclonal Anti-NG2 antibody produced in mouse, clone 132.38, purified immunoglobulin, buffered aqueous solution
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
132.38, monoclonal
form
buffered aqueous solution
species reactivity
rat
technique(s)
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
indirect ELISA: suitable
microarray: suitable
western blot: 1 μg/mL using rat brain neonatal extract
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
rat ... Cspg4(81651)
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Chondroitin sulfate proteoglycan 4 (CSPG4) or nerve/glial antigen 2 (NG2) is a growth-inhibitory chondroitin sulfate proteoglycan (CSPG) produced after spinal cord injury. It has a single glycosaminoglycan (GAG) chain. The protein belongs to the transmembrane chondroitin sulfate proteoglycans family.
Immunogen
cell extract of HEK293 cells expressing the D3 domain of rat NG2.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Application
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)
Western Blotting
Immunohistochemistry (1 paper)
Western Blotting
Biochem/physiol Actions
Chondroitin sulfate proteoglycan 4 (CSPG4) or nerve/glial antigen 2 (NG2) stimulates the activation of integrins in dorsal root ganglion neurons. It also has a role in stimulating inflammatory cytokine expression in microglia.
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저장 등급
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Genetically Engineered Artificial Microvesicles Carrying Nerve Growth Factor Restrains the Progression of Autoimmune Encephalomyelitis in an Experimental Mouse Model.
Alatrash, et al.
International Journal of Molecular Sciences, 24 (2023)
Stefano Di Santo et al.
PloS one, 4(5), e5643-e5643 (2009-05-30)
Current evidence suggests that endothelial progenitor cells (EPC) contribute to ischemic tissue repair by both secretion of paracrine factors and incorporation into developing vessels. We tested the hypothesis that cell-free administration of paracrine factors secreted by cultured EPC may achieve
Antibody-based proteomics for esophageal cancer: Identification of proteins in the nuclear factor-?B pathway and mitotic checkpoint
Norihisa U
Cancer Science (2009)
Entrapment via Synaptic-Like Connections between NG2 Proteoglycan+ Cells and Dystrophic Axons in the Lesion Plays a Role in Regeneration Failure after Spinal Cord Injury
Angela R
The Journal of Neuroscience (2014)
NG2, a member of chondroitin sulfate proteoglycans family mediates the inflammatory response of activated microglia.
Gao Q, ey .al
Neuroscience and Behavioral Physiology (2010)
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