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Merck

P4329

1,2-Dipalmitoyl-sn-glycero-3-phosphocholine

≥99% (TLC)

동의어(들):

PC, (7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxohexadecyl)oxy]- 3,5,9-trioxa-4-phosphapentacosan-1-aminium 4-oxide, inner salt, 1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine, 1,2-Dihexadecanoyl-sn-glycero-3-phosphorylcholine, 1,2-Dipalmitoyl-sn-glycero-3-phosphorylcholine, 1,2-Dipalmitoyl-L-lecithin, L-α-Phosphatidylcholine, dipalmitoyl, L-β,γ-Dipalmitoyl-α-lecithin, DPPC, PC(16:0/16:0)

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크기 선택


제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C40H80NO8P
CAS 번호:
Molecular Weight:
734.04
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352211
EC Number:
200-567-6
MDL number:
기술 서비스
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InChI key

KILNVBDSWZSGLL-KXQOOQHDSA-N

InChI

1S/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3/t38-/m1/s1

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O

biological source

synthetic

assay

≥99% (TLC)

form

powder

functional group

phospholipid

lipid type

phosphoglycerides

shipped in

ambient

storage temp.

−20°C

Quality Level

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관련 카테고리

Application


  • Effects induced by (6)-p-cymene ruthenium(II) complexes on Langmuir monolayers mimicking cancer and healthy cell membranes do not correlate with their toxicity.: This study investigates the interaction of ruthenium(II) complexes with Langmuir monolayers, including 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine, highlighting differences in behavior between cancerous and healthy cell membrane models (Wrobel et al., 2024).

  • Cholesterol Changes Interfacial Water Alignment in Model Cell Membranes.: This study examines how cholesterol affects water alignment at the interface of model cell membranes that include 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine, offering insights into membrane biophysics (Orlikowska-Rzeznik et al., 2024).

  • Impact of Lipid Composition on Vesicle Protein Adsorption: A BSA Case Study.: The impact of different lipid compositions, including 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine, on the adsorption of bovine serum albumin to vesicles is studied to understand protein-lipid interactions (Amarandi et al., 2024).

  • Spatial Arrangement of the Drug Ibuprofen in a Model Membrane in the Presence of Lipid Rafts.: This paper investigates the arrangement of ibuprofen within model membranes containing lipid rafts and 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine, shedding light on drug-membrane interactions (Kashnik et al., 2024).

Other Notes

Purified by crystallization.

저장 등급

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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시험 성적서(COA)

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Photodynamic therapy (PDT) is based on the delivery of photocytotoxic agents to a target tissue, followed by irradiation. In order to increase the efficiency of PDT in oesophageal cancer therapy, polyethylene glycol (PEG)-grafted, transferrin (Tf)-conjugated liposome formulations of 5,10,15,20-tetra(m-hydroxyphenyl)chlorin (Foscan)
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Evidence suggests that synthetic surfactants consisting solely of phospholipids can be improved through the addition of peptides, such as sinapultide, that mimic the action of human surfactant protein-B (SP-B). A synthetic surfactant containing a mimic of SP-B may also reduce
Johannes Thoma et al.
Chemical communications (Cambridge, England), 48(70), 8811-8813 (2012-07-28)
We present a model system to demonstrate that the positioning of biomolecules (membrane proteins) in a nonnative, complex thin film environment can be regulated by the phase behavior of film components. Partial separation between an amphiphilic polymer and a lipid
John M Franck et al.
Journal of the American Chemical Society, 135(11), 4175-4178 (2013-01-26)
The translational hydration dynamics within 0.5-1.5 nm of the surface of a DPPC liposome, a model biomacromolecular surface, is analyzed by the recently developed Overhauser dynamic nuclear polarization (ODNP) technique. We find that dramatic changes to the bulk solvent cause
Agustín Mangiarotti et al.
Biochimica et biophysica acta, 1838(7), 1823-1831 (2014-03-04)
For the biophysical study of membranes, a variety of model systems have been used to measure the different parameters and to extract general principles concerning processes that may occur in cellular membranes. However, there are very few reports in which

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