콘텐츠로 건너뛰기
Merck

P6004

Prednisolone

≥99% (HPLC), powder, glucocorticoid

동의어(들):

1,4-Pregnadiene-11β,17α,21-triol-3,20-dione, 1-Dehydrocortisol, 1-Dehydrohydrocortisone, 11β,17α,21-Trihydroxy-1,4-pregnadiene-3,20-dione

조직 및 계약 가격을 보려면 로그인를 클릭합니다.

크기 선택

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C21H28O5
CAS 번호:
50-24-8
Molecular Weight:
360.44
NACRES:
NA.77
PubChem Substance ID:
24898725
UNSPSC Code:
12352200
EC Number:
200-021-7
MDL number:
MFCD00003649
Beilstein/REAXYS Number:
1354103
Assay:
≥99%
Form:
powder
Quality level:
200

주요 문서

모든 문서 보기
기술 서비스
도움이 필요하신가요? 저희 숙련된 과학자 팀이 도와드리겠습니다.
도움 문의
기술 서비스
도움이 필요하신가요? 저희 숙련된 과학자 팀이 도와드리겠습니다.
도움 문의

제품 이름

Prednisolone, ≥99%

InChI

1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-16,18,22,24,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1

SMILES string

O=C1C=C[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C)[C@@]3([H])CC[C@]4(O)C(CO)=O)=C1

InChI key

OIGNJSKKLXVSLS-VWUMJDOOSA-N

biological source

synthetic (organic)

sterility

non-sterile

assay

≥99%

form

powder

mp

240 °C (dec.) (lit.)

solubility

chloroform: methanol (1:1): 50 mg/mL, clear, colorless to faintly yellow

originator

Johnson & Johnson

shipped in

ambient

storage temp.

room temp

Quality Level

200

Gene Information

human ... AR(367), ESR1(2099), NR3C1(2908), NR3C2(4306), PGR(5241), SERPINA6(866)
mouse ... Nr3c1(14815)
rat ... Ar(24208)

유사한 제품을 찾으십니까? 방문 제품 비교 안내

관련 카테고리

General description

Prednisolone prevents protease activity in vitro. It stimulates myogenesis and inhibits apoptosis. Prednisolone is used to treat Duchenne muscular dystrophy (DMD), gout arthritis and chronic obstructive pulmonary disease (COPD) exacerbations.

Application

Prednisolone has been used for the Δ1-dehydrogenation of hydrocortisone by gel entrapped arthrobacter simplex cells.

Biochem/physiol Actions

Prednisolone is a glucocorticoid with anti-inflammatory and immunosuppressive activity.

Features and Benefits

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Analysis Note

Actual content given on label

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H360FD

Hazard Classifications

Repr. 1B

저장 등급

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

ppe

dust mask type N95 (US), Eyeshields, Gloves

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
0000499317
0000499317
0000446723
0000446717
0000446716

적합한 버전을 찾을 수 없으신가요?

특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

COA 검색

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Oral or IV Prednisolone in the Treatment of COPD Exacerbations
de Jong YP, et al.
Chest, 132(6), 1741-1747 (2007)
Use of oral prednisolone or naproxen for the treatment of gout arthritis: a double-blind, randomised equivalence trial
Janssens HJEM, et al.
Lancet, 371(9627), 1854-1860 (2008)
Paul M L Janssen et al.
PloS one, 9(2), e88360-e88360 (2014-02-20)
Duchenne muscular dystrophy (DMD) is an inherited disease that causes striated muscle weakness. Recently, we showed therapeutic effects of the combination of lisinopril (L), an angiotensin converting enzyme (ACE) inhibitor, and spironolactone (S), an aldosterone antagonist, in mice lacking dystrophin
Kang Ho Kim et al.
Molecular endocrinology (Baltimore, Md.), 30(8), 905-916 (2016-06-30)
Liver fibrosis is a reversible wound-healing process that is protective in the short term, but prolonged fibrotic responses lead to excessive accumulation of extracellular matrix components that suppresses hepatocyte regeneration, resulting in permanent liver damage. Upon liver damage, nonparenchymal cells
Continuous non-aerated Delta 1-dehydrogenation of hydrocortisone by PAAH-bead entrapped Arthrobacter simplex
Silbiger E and Freeman A
Applied Microbiology and Biotechnology, 29(5), 413-418 (1988)
모든 관련된 서류 보기

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

고객지원팀으로 연락바랍니다.