조직 및 계약 가격을 보려면 로그인를 클릭합니다.
크기 선택
보기 변경
제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
C6H5CH2N(CH3)CH2C≡CH·HCl
CAS 번호:
Molecular Weight:
195.69
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
206-175-1
MDL number:
Beilstein/REAXYS Number:
3699487
제품 이름
Pargyline hydrochloride,
biological source
synthetic
Quality Level
assay
98% (TLC)
form
powder or crystals
mp
160-163 °C (lit.)
solubility
water: 50 mg/mL, clear, colorless to faintly yellow
storage temp.
−20°C
SMILES string
Cl[H].CN(CC#C)Cc1ccccc1
InChI
1S/C11H13N.ClH/c1-3-9-12(2)10-11-7-5-4-6-8-11;/h1,4-8H,9-10H2,2H3;1H
InChI key
BCXCABRDBBWWGY-UHFFFAOYSA-N
Gene Information
human ... MAOA(4128), MAOB(4129)
Application
Pargyline hydrochloride has been used:
- as a histone demethylase inhibitor to treat monocytes to investigate whether various inhibitors affect training
- to maximize uptake into dopaminergic neurons (DA) neurons in experimental rats,
- to study its effect on discolouration of medullary tissues of sclerotia of S. sclerotiorum
Biochem/physiol Actions
Pargyline hydrochloride acts as a histone demethylase inhibitor. It has antihypertensive action.
Selective MAO-B inhibitor.
signalword
Danger
hcodes
pcodes
Hazard Classifications
Acute Tox. 3 Oral
저장 등급
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Biochemical Pathway for the Formation of Abnormal Sclerotia of Sclerotinia sclerotiorum
Huang HC and Yeung JM
Plant Pathology, 11(1), 2-2 (2002)
Trained immunity or tolerance: opposing functional programs induced in human monocytes after engagement of various pattern recognition receptors
Ifrim DC, et al.
Clinical and Vaccine Immunology : CVI, 21(4), 534-545 (2014)
An update on antidepressant toxicity: an evolution of unique toxicities to master
Liebelt EL
Clinical Pediatric Emergency Medicine, 9(1), 24-34 (2008)
