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Merck

P8877

D-(−)-3-Phosphoglyceric acid disodium salt

greener alternative

≥93% dry basis (enzymatic), powder

동의어(들):

(−)-Disodium D-3-phosphoglycerate, D-Glycerate 3-phosphate disodium salt

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크기 선택


제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C3H5Na2O7P
CAS 번호:
Molecular Weight:
230.02
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3767836
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InChI key

RGCJWQYUZHTJBE-YBBRRFGFSA-L

SMILES string

[Na+].[Na+].O[C@H](COP(O)([O-])=O)C([O-])=O

InChI

1S/C3H7O7P.2Na/c4-2(3(5)6)1-10-11(7,8)9;;/h2,4H,1H2,(H,5,6)(H2,7,8,9);;/q;2*+1/p-2/t2-;;/m1../s1

biological source

synthetic (inorganic)

assay

≥93% dry basis (enzymatic)

form

powder

greener alternative product characteristics

Atom Economy
Design for Energy Efficiency
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

impurities

<14% water (NMR)

color

white

solubility

H2O: 50 mg/mL, clear, colorless to faintly yellow

cation traces

Na: 18-22% (dry basis)

greener alternative category

storage temp.

−20°C

Quality Level

Application

D-(-)-3-Phosphoglyceric acid disodium salt has been used in a study to assess the phosphorylation of glyceric acid in aqueous solution. It has also been used in a study to characterize a glutathione- and NAD-dependent arsenate reduction linked to glycolysis.

Biochem/physiol Actions

3-Phosphoglyceric acid is an intermediate in glycolysis. It also a precursor in the formation of serine.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

pictograms

Health hazardExclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 2 - STOT SE 3

target_organs

Eyes,Central nervous system, Respiratory system

저장 등급

11 - Combustible Solids

wgk

WGK 3


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시험 성적서(COA)

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문서 라이브러리 방문

Balázs Németi et al.
Toxicological sciences : an official journal of the Society of Toxicology, 85(2), 847-858 (2005-03-25)
Reduction of arsenate (AsV) to the more toxic arsenite (AsIII) is of high toxicological importance, yet in vivo relevant enzymes involved have not been identified. Purine nucleoside phosphorylase (PNP) is an efficient AsV reductase in vitro, but its role in
V Kolb et al.
Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 26(1), 7-13 (1996-02-01)
The phosphorylation of glyceric acid is an interesting prebiotic reaction because it converts a simple, potentially prebiotic organic molecule into phosphate derivatives that are central to carbohydrate metabolism. We find that 0.05 M glyceric acid in the presence of 0.5
Jeremy M Foster et al.
PloS one, 5(10), e13576-e13576 (2010-12-29)
The glycolytic phosphoglycerate mutases exist as non-homologous isofunctional enzymes (NISE) having independent evolutionary origins and no similarity in primary sequence, 3D structure, or catalytic mechanism. Cofactor-dependent PGM (dPGM) requires 2,3-bisphosphoglycerate for activity; cofactor-independent PGM (iPGM) does not. The PGM profile
Yinhua Zhang et al.
The Journal of biological chemistry, 279(35), 37185-37190 (2004-07-06)
Phosphoglycerate mutases catalyze the interconversion of 2- and 3-phosphoglycerate in the glycolytic and gluconeogenic pathways. They exist in two unrelated forms that are either cofactor (2,3-diphosphoglycerate)-dependent or cofactor-independent. The two enzymes have no similarity in amino acid sequence, tertiary structure
Maria V Liberti et al.
Cell metabolism, 26(4), 648-659 (2017-09-19)
Targeted cancer therapies that use genetics are successful, but principles for selectively targeting tumor metabolism that is also dependent on the environment remain unknown. We now show that differences in rate-controlling enzymes during the Warburg effect (WE), the most prominent

문서

Review the 10 steps of glycolysis in the Embden-Meyerhof-Parnas glycolytic pathway. Easily compare reaction stages and buy the enzymes for your life science research.

Warburg effect enhances glucose to lactate conversion in tumor cells, regardless of oxygen levels; impacting cancer metabolism since 1924.

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