S0266

Spermidine

Name: Spermidine
Brand: SIGMA

BioReagent, Molecular Biology, suitable for cell culture, ≥98%

동의어(들):

1,8-Diamino-4-azaoctane, N-(3-Aminopropyl)-1,4-diaminobutane

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크기 선택

제품정보 (DICE 배송 시 비용 별도)

Linear Formula:

NH₂(CH₂)₃NH(CH₂)₄NH₂

CAS 번호:

124-20-9

Molecular Weight:

145.25

UNSPSC Code:

12352200

NACRES:

NA.52

PubChem Substance ID:

24899434

EC Number:

204-689-0

Beilstein/REAXYS Number:

1698591

MDL number:

MFCD00008229

주요 문서

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InChI key

ATHGHQPFGPMSJY-UHFFFAOYSA-N

InChI

1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2

SMILES string

NCCCCNCCCN

grade

Molecular Biology

product line

BioReagent

assay

≥98%

form

solid or liquid

mol wt

145.25 (AMU)

technique(s)

cell culture | mammalian: suitable

refractive index

n20/D 1.479 (lit.)

density

0.925 g/mL at 25 °C (lit.)

foreign activity

DNase, RNase, and protease, none detected

storage temp.

room temp

Quality Level

200

Gene Information

rat ... Ppm1a(24666)

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General description

Spermidine belongs to the natural polyamines, that are found in chloroplasts and in bacterial or eukaryotic cells.

Application

Spermidine has been used in the preparation of gold beads and as a component in nuclei isolation buffer (NIB).

Spermidine is suitable for use in molecular biology buffers and for precipitation of DNA >100 bp in length. It was used to deliver DNA in plants and mammalian cells by particle bombardment technique.

Biochem/physiol Actions

Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; Stimulates T₄ polynucleotide kinase activity.

Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T₄ polynucleotide kinase activity.

Spermidine helps to maintain the proper activity of gene expression. This polyamine plays a key role in intermediate metabolism. It also serves as an inhibitor of the acetyl transferase activity of E1A-associated protein p300 (EP300). Spermidine participates in cell growth.

Disclaimer

Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.

pictograms

GHS05

signalword

Danger

hcodes

H314

pcodes

P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

저장 등급

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

233.6 °F - closed cup

flash_point_c

112 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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문서 라이브러리 방문

Organization, developmental dynamics, and evolution of plastid nucleoids

Sato N, et al.

International Review of Cytology, 232, 217-262 (2003)

Spermidine delays aging in humans

Madeo F, et al.

Aging (Albany. NY.), 10(8), 2209-2209 (2018)

Protamine-mediated DNA coating remarkably improves bombardment transformation efficiency in plant cells.

Elumalai Sivamani et al.

Plant cell reports, 28(2), 213-221 (2008-11-19)

We have developed a method by which remarkably higher efficiencies of transient and stable transformation were achieved in bombardment transformation of plants. Over fivefold increase in transient gus gene expression was achieved when rice or maize suspension cells were bombarded

Delivery of DNA to skin by particle bombardment.

Shixia Wang et al.

Methods in molecular biology (Clifton, N.J.), 245, 185-196 (2004-01-07)

Molecular Determinants of Metaplastic and Neoplastic Transformation in the Esophageal Epithelium

Progress in Molecular Biology and Translational Science, 96, 63-92 (2010)

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자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

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Spermidine

BioReagent, Molecular Biology, suitable for cell culture, ≥98%

크기 선택

제품정보 (DICE 배송 시 비용 별도)

주요 문서

속성

InChI key

InChI

SMILES string

grade

product line

assay

form

mol wt

technique(s)

refractive index

density

foreign activity

storage temp.

Quality Level

Gene Information

설명

General description

Application

Biochem/physiol Actions

Disclaimer

안전성 정보

pictograms

signalword

hcodes

pcodes

Hazard Classifications

저장 등급

wgk

flash_point_f

flash_point_c

ppe

문서

시험 성적서(COA)

이 제품을 이미 가지고 계십니까?

관련 참고 논문

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