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Merck

S2501

Spermidine trihydrochloride

From microbial,synthetic, ≥98% (TLC), nNOS inhibitor, powder

동의어(들):

N-(3-Aminopropyl)-1,4-butanediamine trihydrochloride

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
NH2(CH2)3NH(CH2)4NH2 · 3HCl
CAS 번호:
Molecular Weight:
254.63
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
206-379-0
MDL number:
Beilstein/REAXYS Number:
3552356
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제품 이름

Spermidine trihydrochloride, ≥98% (TLC)

InChI key

LCNBIHVSOPXFMR-UHFFFAOYSA-N

InChI

1S/C7H19N3.3ClH/c8-4-1-2-6-10-7-3-5-9;;;/h10H,1-9H2;3*1H

SMILES string

Cl[H].Cl[H].Cl[H].NCCCCNCCCN

biological source

microbial, synthetic

assay

≥98% (TLC)

form

powder

mp

257-259 °C (lit.)

solubility

water: 100 mg/mL, clear, colorless

storage temp.

room temp

Quality Level

Gene Information

human ... NOS1(4842)

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General description

The nitric oxide synthase (nNOS) gene is localized on human chromosome 12q24.22. The enzyme is involved in the production of nitric oxide.

Application

Spermidine trihydrochloride has been used in fourier transform infrared spectroscopy (FTIR)characterization and in zeta-potential measurements.

Biochem/physiol Actions

Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; Stimulates T4 polynucleotide kinase activity.
Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T4 polynucleotide kinase activity.

Disclaimer

Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

저장 등급

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Physical interactions between DNA and sepiolite nanofibers, and potential application for DNA transfer into mammalian cells.
Castro-Smirnov FA
Scientific Reports, 6, 36341-36341 (2016)
Ayesha Kabir et al.
Biochimica et biophysica acta. General subjects, 1864(5), 129557-129557 (2020-02-12)
Polyamines can induce protein aggregation that can be related to the physiology of the cellular function. Polyamines have been implicated in protein aggregation which may lead to neuropathic and non neuropathic amyloidosis. Change in the level of polyamine concentration has
Evidence for the contribution of NOS1 gene polymorphism (rs3782206) to prefrontal function in schizophrenia patients and healthy controls.
Zhang Z
Neuropsychopharmacology, 40(6), 1383-1394 (2015)
Miao Cui et al.
STAR protocols, 1(2), 100049-100049 (2020-10-29)
Murine cardiomyocytes undergo proliferation, multinucleation, and polyploidization during the first 3 weeks of postnatal life, resulting in a mixture of diploid and tetraploid cardiomyocytes in the heart. Understanding the molecular differences between diploid and tetraploid cardiomyocytes from these processes has been
Generating transgenic frog embryos by restriction enzyme mediated integration (REMI).
Ishibashi S
Methods in Molecular Biology, 917, 185-203 (2012)

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