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Merck

S7635

Sulforhodamine 101

Dye content ~95 %, Powder

동의어(들):

SR101; 2-(3-oxa-23-aza-9-azoniaheptacyclo[17.7.1.15,9.02,17.04,15.023,27.013,28]octacosa-1(27),2(17),4,9(28),13,15,18-heptaen-16-yl)-5-sulfobenzenesulfonate

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C31H30N2O7S2
CAS 번호:
Molecular Weight:
606.71
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
262-159-4
MDL number:
Beilstein/REAXYS Number:
3582548
기술 서비스
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제품 이름

Sulforhodamine 101, Dye content ~95 %

InChI

1S/C31H30N2O7S2/c34-41(35,36)20-9-10-21(26(17-20)42(37,38)39)27-24-15-18-5-1-11-32-13-3-7-22(28(18)32)30(24)40-31-23-8-4-14-33-12-2-6-19(29(23)33)16-25(27)31/h9-10,15-17H,1-8,11-14H2,(H-,34,35,36,37,38,39)

InChI key

COIVODZMVVUETJ-UHFFFAOYSA-N

SMILES string

OS(=O)(=O)c1ccc(C2=C3C=C4CCC[N+]5=C4C(CCC5)=C3Oc6c7CCCN8CCCc(cc26)c78)c(c1)S([O-])(=O)=O

form

powder

composition

Dye content, ~95%

technique(s)

microbe id | staining: suitable

color

black
dark green to brown

solubility

methanol: 1 mg/mL

ε (extinction coefficient)

≥105000 at 573-579 nm in ethanol

fluorescence

λex 586 nm; λem 605 nm in H2O

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

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Application

Sulforhodamine 101 has been used:
  • to label astrocytes
  • in quantitative polymerase chain reaction (PCR)
  • to determine the degree of disintegration in tissue sample

Biochem/physiol Actions

Sulforhodamine 101 can be specifically used as a marker of astroglia in the neocortex. It is commonly used for brain imaging. Studies suggest that sulforhodamine 101 may be used as an epileptogenic agent.

General description

Sulforhodamine 101 is a red fluorescent dye. It is water-soluble, amphoteric rhodamine.

저장 등급

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Jumpei Ukita et al.
Scientific reports, 9(1), 3791-3791 (2019-03-09)
A comprehensive understanding of the stimulus-response properties of individual neurons is necessary to crack the neural code of sensory cortices. However, a barrier to achieving this goal is the difficulty of analysing the nonlinearity of neuronal responses. Here, by incorporating
Danielle Tokarz et al.
PloS one, 12(10), e0186846-e0186846 (2017-10-25)
Osteocytes are the most abundant cell in the bone, and have multiple functions including mechanosensing and regulation of bone remodeling activities. Since osteocytes are embedded in the bone matrix, their inaccessibility makes in vivo studies problematic. Therefore, a non-invasive technique
Florence Appaix et al.
PloS one, 7(4), e35169-e35169 (2012-04-18)
Fluorescent staining of astrocytes without damaging or interfering with normal brain functions is essential for intravital microscopy studies. Current methods involved either transgenic mice or local intracerebral injection of sulforhodamine 101. Transgenic rat models rarely exist, and in mice, a
In vivo imaging of oligodendrocytes with sulforhodamine 101
Hill RA and Grutzendler J
Nature Methods, 11(11), 1081-1081 (2014)
David S Greenberg et al.
Nature neuroscience, 11(7), 749-751 (2008-06-17)
It is unclear how the complex spatiotemporal organization of ongoing cortical neuronal activity recorded in anesthetized animals relates to the awake animal. We therefore used two-photon population calcium imaging in awake and subsequently anesthetized rats to follow action potential firing

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