S9549
Superoxide dismutase–polyethylene glycol from bovine erythrocytes
lyophilized powder, ≥1,350 units/mg protein
동의어(들):
PEG-SOD
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크기 선택
보기 변경
제품정보 (DICE 배송 시 비용 별도)
Specific activity:
≥1,350 units/mg protein
General description
Superoxide dismutase from bovine erythrocytes is a copper and zinc superoxide dismutase. Copper and zinc ions are coordinated by active site histidine residues. It has β-barrel structure.
Application
Superoxide dismutase-polyethylene glycol from bovine erythrocytes has been used:
- in the incubation of lung slices for measurement of dihydroethidium (DHE) fluorescence in cultured bovine pulmonary artery endothelial cells
- as supplement in T cell culture to investigate its effect on cytokine production
- in the preincubation of the carotid artery sections prior to DHE treatment
Biochem/physiol Actions
Superoxide dismutase-polyethylene glycol (SOD-PEG) is effective than SOD in scavenging free radicals in injuries. It reduces oxidative damage in ovarian follicles cell culture and during ovarian tissue transplantation. SOD-PEG is also effective in scavenging superoxide in mitochondrial abnormalities.
Packaging
Package size based on protein content
Physical form
Lyophilized powder containing PEG plus 5% citrate buffer salts
Preparation Note
Enzyme derived
Other Notes
Superoxide dismutase from bovine erythrocytes coupled to methoxy-polyethylene glycol, M.W. 5,000, through secondary amine linkage.
signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Simone R Potje et al.
Free radical biology & medicine, 112, 587-596 (2017-09-14)
[Ru(terpy)(bdq)NO]
Roles of zinc and copper in modulating the oxidative refolding of bovine copper, zinc superoxide dismutase
Li HT, et al.
Acta biochimica et biophysica Sinica, 42(3), 183-194 (2010)
Role of increased guanosine triphosphate cyclohydrolase-1 expression and tetrahydrobiopterin levels upon T cell activation
Chen W, et al.
The Journal of Biological Chemistry, 286, 13846-13851 (2011)