SAB1306281

ANTI-SNAIL (N-TERM D24) antibody produced in rabbit

Name: ANTI-SNAIL (N-TERM D24) antibody produced in rabbit
Brand: SIGMA

IgG fraction of antiserum, buffered aqueous solution

동의어(들):

Protein snail homolog 1, SNAH, SNAI1, Zinc finger protein SNAI1

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크기 선택

제품정보 (DICE 배송 시 비용 별도)

NACRES:

NA.41

UNSPSC Code:

12352203

Clone:

polyclonal

Species reactivity:

human

Application:

immunohistochemistry
western blot

Technique(s):

immunohistochemistry: 1:10-1:50
western blot: 1:1000

Citations:

Uniprot accession no.:

O95863

주요 문서

모든 문서 보기

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제품 이름

ANTI-SNAIL (N-TERM D24) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution

biological source

rabbit

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

29083 Da

species reactivity

human

technique(s)

immunohistochemistry: 1:10-1:50
western blot: 1:1000

NCBI accession no.

NP_005976.2

UniProt accession no.

O95863

application(s)

research pathology

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... SNAI1(6615)

Application

ANTI-SNAIL (N-TERM D24) antibody produced in rabbit has been used in Western Blotting.

Biochem/physiol Actions

Snail family transcriptional repressor 1 (SNAIL) acts as a repressor of genes associated with the epithelial phenotype like E-cadherin and increases the expression of genes linked with the mesenchymal phenotype. It has a role in epithelial-mesenchymal transition. The protein aids in G1 transition (early to late) in the cell cycle. SNAIL also modulates cell-matrix adhesion.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Snail family transcriptional repressor 1 (SNAIL) is a transcription factor and the gene encoding it is localized on human chromosome 20q13.13.

Physical form

Supplied in PBS with 0.09% (W/V) sodium azide

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저장 등급

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number

SH021021H

SG021021H

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특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

COA 검색

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

TP53 Mutation, Epithelial-Mesenchymal Transition, and StemlikeFeatures in Breast Cancer Subtypes

Danila Coradini

Journal of Biomedicine and Biotechnology (2013)

CRISPR/Cas9n-Mediated Deletion of the Snail 1Gene (SNAI1) Reveals Its Role in Regulating Cell Morphology, Cell-Cell Interactions, and Gene Expression in Ovarian Cancer (RMG-1) Cells.

Haraguchi M

PLoS ONE, 10(7) (2015)

Biochanin A extirpates the epithelial-mesenchymal transition in a human lung cancer

Wang Yan

Experimental and Therapeutic Medicine, 2830-2836 (2018)

SNAIL transcription factor increases the motility and invasive capacity of prostate cancer cells.

Osorio LA

Molecular Medicine Reports, 13(1), 778-786 (2016)

The metastasis suppressor, NDRG1, attenuates oncogenic TGF-β and NF-κB signaling to enhance membrane E-cadherin expression in pancreatic cancer cells.

Sharleen V Menezes et al.

Carcinogenesis, 40(6), 805-818 (2018-12-19)

The metastasis suppressor, N-myc downstream-regulated gene-1 (NDRG1), plays multifaceted roles in inhibiting oncogenic signaling and can suppress the epithelial mesenchymal transition (EMT), a key step in metastasis. In this investigation, NDRG1 inhibited the oncogenic effects of transforming growth factor-β (TGF-β)

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ANTI-SNAIL (N-TERM D24) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

크기 선택

제품정보 (DICE 배송 시 비용 별도)

주요 문서

속성

제품 이름

biological source

antibody form

antibody product type

clone

form

mol wt

species reactivity

technique(s)

NCBI accession no.

UniProt accession no.

application(s)

shipped in

storage temp.

target post-translational modification

Quality Level

Gene Information

설명

Application

Biochem/physiol Actions

Disclaimer

General description

Physical form

안전성 정보

저장 등급

flash_point_f

flash_point_c

문서

시험 성적서(COA)

이 제품을 이미 가지고 계십니까?

관련 참고 논문

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