SAB4300541

Anti-HSP90AB1 (Ab-254) antibody produced in rabbit

Name: Anti-HSP90AB1 (Ab-254) antibody produced in rabbit
Brand: SIGMA

affinity isolated antibody

동의어(들):

Anti-D6S182 antibody produced in rabbit, Anti-FLJ26984 antibody produced in rabbit, Anti-HSP90-BETA antibody produced in rabbit, Anti-HSP90B antibody produced in rabbit, Anti-heat shock protein 90kDa alpha (cytosolic), class B member 1 antibody produced in rabbit

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크기 선택

제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD07370344

Conjugate:

unconjugated

Clone:

polyclonal

Application:

IF, IHC (p), WB

Citations:

주요 문서

모든 문서 보기

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도움 문의

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~92 kDa

species reactivity

mouse, rat, human

concentration

1 mg/mL

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100, indirect immunofluorescence: 1:100-1:200, western blot: 1:500-1:1000

isotype

IgG

immunogen sequence

(V-G-S-D-E)

NCBI accession no.

NP_031381.2

UniProt accession no.

P08238

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... HSP90AB1(3326)

General description

HSP90AB1 (heat shock protein 90 αfamily class B member 1) belongs to the Hsp90 family. It consists of major members-Hsp90α, Hsp90β, GRP94 (glucose-regulated protein 94) and Hsp75. It is located on chromosome 6p21. It is an ATP-dependent molecular chaperone, that is of 90kDa.

Molecular chaperone. Has ATPase activity.

Immunogen

Peptide sequence around aa. 252-256 (V-G-S-D-E), according to the protein HSP90AB1.

Biochem/physiol Actions

HSP90AB1 (heat shock protein 90 αfamily class B member 1) participates in signal transduction, protein folding and degradation, and morphological evolution. It is required for the transport of client proteins between the cytoplasm and nucleus. In lung adenocarcinoma patients, overexpression of HSP90AB1 in non-small cell lung cancer tissues results in imperfect clinical predictions. Suppression of this gene reduces the potential of endothelial cells to form tube structures.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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저장 등급

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number

951421290

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특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

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문서 라이브러리 방문

A novel variant on chromosome 6p21.1 is associated with the risk of developing colorectal cancer: a two-stage case-control study in Han Chinese

Xu C, et al.

BMC Cancer, 16(1), 807-807 (2016)

[Hsp90AB1 Protein is Overexpressed in Non-small Cell Lung Cancer Tissues ?and Associated with Poor Prognosis in Lung Adenocarcinoma Patients]

Wang M, et al.

Zhongguo Fei ai za Zhi = Chinese Journal of Lung Cancer, 19(2), 64-69 (2016)

Partial Rescue of F508del-CFTR Stability and Trafficking Defects by Double Corrector Treatment.

Valeria Capurro et al.

International journal of molecular sciences, 22(10) (2021-06-03)

Deletion of phenylalanine at position 508 (F508del) in the CFTR chloride channel is the most frequent mutation in cystic fibrosis (CF) patients. F508del impairs the stability and folding of the CFTR protein, thus resulting in mistrafficking and premature degradation. F508del-CFTR

Hsp90? promoted endothelial cell-dependent tumor angiogenesis in hepatocellular carcinoma

Meng J, et al.

Molecular Cancer, 16(1), 72-72 (2017)

Dramatic enhancement of the detection limits of bioassays via ultrafast deposition of polydopamine.

Junwei Li et al.

Nature biomedical engineering, 1 (2017-10-31)

The ability to detect biomarkers with ultrahigh sensitivity radically transformed biology and disease diagnosis. However, owing to incompatibilities with infrastructure in current biological and medical laboratories, recent innovations in analytical technology have not received broad adoption. Here, we report a

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Anti-HSP90AB1 (Ab-254) antibody produced in rabbit

affinity isolated antibody

크기 선택

제품정보 (DICE 배송 시 비용 별도)

주요 문서

속성

biological source

conjugate

antibody form

antibody product type

clone

form

mol wt

species reactivity

concentration

technique(s)

isotype

immunogen sequence

NCBI accession no.

UniProt accession no.

shipped in

storage temp.

target post-translational modification

Quality Level

Gene Information

설명

General description

Immunogen

Biochem/physiol Actions

Features and Benefits

Physical form

Disclaimer

안전성 정보

저장 등급

wgk

flash_point_f

flash_point_c

문서

시험 성적서(COA)

이 제품을 이미 가지고 계십니까?

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