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Merck

SAB4502609

Anti-NF-κB p65 antibody produced in rabbit

affinity isolated antibody

동의어(들):

NFKB3, RELA, TF65, nuclear factor NF-κ-B p65 subunit, p65

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제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, WB
Citations:
17
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 60 kDa

species reactivity

human, mouse

concentration

~1 mg/mL

technique(s)

ELISA: 1:20000, western blot: 1:500-1:1000

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... RELA(5970)

General description

Anti-NF-κB p65 antibody detects endogenous levels of total NF-κB p65 protein.
The NF-κB p65 (nuclear factor κ-light-chain-enhancer of activated B cells p65) gene is mapped to human chromosome 11q13.1. It codes for a transcription factor, a subunit of NF-κB.

Immunogen

The antiserum was produced against synthesized peptide derived from human NF-kappaB p65.

Immunogen Range: 278-327

Application

Anti-NF-κB p65 antibody produced in rabbit has been used in western blot analysis.

Biochem/physiol Actions

NF-κB p65 (nuclear factor κ-light-chain-enhancer of activated B cells p65) is associated with many fibrotic diseases such as liver fibrosis and cardiac fibrosis. Cell proliferation, inflammation, and apoptosis are some of the processes mediated by NF-κB p65. Dysregulation of the gene results in chronic inflammatory diseases, autoimmune disorders and cancer. NF-κB p65 plays an important role in NF-κB signaling.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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저장 등급

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable



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문서 라이브러리 방문



Danshensu protects against ischemia/reperfusion injury and inhibits the apoptosis of H9c2 cells by reducing the calcium overload through the p-JNK-NF-?B-TRPC6 pathway.
Meng Y
International Journal of Molecular Medicine, 37(1), 258-266 (2016)
The role of hyperuricemia on vascular endothelium dysfunction.
Zhen H and Gui F
Biomedical Reports, 7(4), 325-330 (2017)
RelA/p65 inhibition prevents tendon adhesion by modulating inflammation, cell proliferation, and apoptosis.
Chen S
Cell Death & Disease, 8(3), 1-13 (2017)