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Merck

T3309

Transferrin human

≥98%

동의어(들):

Siderophilin, partially saturated

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제품정보 (DICE 배송 시 비용 별도)

CAS 번호:
UNSPSC Code:
12352202
EC Number:
234-318-8
NACRES:
NA.61
MDL number:
Form:
powder
Assay:
≥98%
Biological source:
human
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제품 이름

Transferrin human, ≥98%

biological source

human

assay

≥98%

form

powder

Iron content

300-600 ppm

technique(s)

cell culture | stem cell: suitable

impurities

≤1.0 EU/mg endotoxin

UniProt accession no.

storage temp.

2-8°C

Quality Level

Gene Information

human ... TF(7018)

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Analysis Note

Purity by agarose electrophoresis.

Application

Transferrin has been used:
  • in isolation of epidermal stem cells and cell expansion
  • to study the effect of compound treatment on transferrin uptake
  • for transferrin uptake and confocal imaging

Biochem/physiol Actions

Transferrin facilitates the transfer of iron to erythron and peripheral tissues. Mutations in this gene is associated with atransferrinemia. Transferrin is required for fetal development. It is non immunogenic and transferrin-conjugated drugs inhibits cardiotoxicity and drug resistance.
Transferrin was shown to promote the proliferation of human lymphocytes. This effect is directly proportional to the level of iron present.

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

General description

Transferrin is an 80 kDa serum glycoprotein, which has an half-life of 8 to 10 days. The gene is located on human chromosome 3q22.1. Transferrin is expressed in hepatocytes.

저장 등급

11 - Combustible Solids

wgk

WGK 3


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Non-invasive in vivo imaging of near infrared-labeled transferrin in breast cancer cells and tumors using fluorescence lifetime FRET
Abe K, et al.
PLoS ONE, 8(11), e80269-e80269 (2013)
A Djeha et al.
British journal of haematology, 80(2), 235-241 (1992-02-01)
The effect of different forms of iron and iron-binding proteins on the proliferative response of human lymphocytes to phytohaemagglutinin (PHA) has been studied. Transferrin enhanced proliferation, the effect being proportional to the degree of iron saturation up to 100%, but
TFRC (transferrin receptor (p90, CD71))
Dorak MT
Atlas of Genetics and Cytogenetics in Oncology and Haematology (2009)
Severe hypochromic microcytic anemia in a patient with congenital atransferrinemia
Shamsian BS, et al.
Pediatric Hematology and Oncology, 26(5), 356-362 (2009)
Nutritional issues in the patient with diabetes and foot ulcers
LITCHFORD MD
Levin and O'Neal's The Diabetic Foot, 199-217 (2008)

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Product Information Sheet

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