U6750
Uridine 5′-triphosphate trisodium salt hydrate
≥93.0% (HPLC), Thyroid hormone
동의어(들):
UTP Na3
조직 및 계약 가격을 보려면 로그인를 클릭합니다.
크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C9H12N2Na3O15P3 · xH2O
CAS 번호:
Molecular Weight:
550.09 (anhydrous basis)
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
243-347-5
MDL number:
Beilstein/REAXYS Number:
3585234
Assay:
≥93.0% (HPLC)
Quality level:
제품 이름
Uridine 5′-triphosphate trisodium salt hydrate, Type IV, ≥93.0% (HPLC)
InChI key
MMJGIWFJVDOPJF-LLWADOMFSA-K
InChI
1S/C9H15N2O15P3.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18);;;/q;3*+1/p-3/t4-,6-,7-,8-;;;/m1.../s1
SMILES string
[Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)N2C=CC(=O)NC2=O
type
Type IV
assay
≥93.0% (HPLC)
solubility
H2O: soluble 25 mg of UTP in 0.5 ml of solvent, clear, colorless
storage temp.
−20°C
Quality Level
유사한 제품을 찾으십니까? 방문 제품 비교 안내
Application
UTP has been used as a P2 receptor activator to study its effects on proton efflux in MC3T3-E1 and UMR-106 cells. UTP has also been studied in combination with amiloride hydrochloride in nebulizer solutions for treating cystic fibrosis.
Uridine 5′-triphosphate has been used in a study to show that fluoxetine (FLX), mediates its anti-depressive effect by increasing the gliotransmission of adenosine 5′-triphosphate (ATP).
Biochem/physiol Actions
P2Y receptor agonist.
Uridine-5′-Triphosphate (UTP) is a cytosolic nucleotide component of nucleic acids. It serves as a signaling molecule in the extracellular space. Uridine-5′-Triphosphate (UTP) is involved in various pathophysiological responses in the nervous system. UTP also plays a major role in the regeneration process.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Preparation Note
25 mg of Uridine 5′-triphosphate trisodium salt (UTP Na3) hydrate is soluble in 0.5 ml of water and yields a clear, colorless solution.
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Uridine-5?-Triphosphate Partially Blocks Differentiation Signals and Favors a more Repair State in Cultured rat Schwann Cells
Palomo-Guerrero M, et al.
Neuroscience, 372(2), 255-265 (2018)
Anti-Depressant Fluoxetine Reveals its Therapeutic Effect Via Astrocytes
Kinoshita M, et al.
EBioMedicine, 372(2), 255-265 (2018)
Ronald J Pettis et al.
Journal of pharmaceutical sciences, 93(9), 2399-2406 (2004-08-06)
Combination therapy using nebulized amiloride hydrochloride and uridine-5'-triphosphate (UTP) trisodium salt aerosols has been investigated for the treatment of cystic fibrosis (CF). Amiloride in aqueous solution precipitates in the presence of UTP, reducing drug concentrations. Interactions between these drugs and
Intralesional uridine-5?-triphosphate (UTP) treatment induced resistance to Leishmania amazonensis infection by boosting Th 1 immune responses and reactive oxygen species production
Marques-da-Silva C, et al.
Purinergic Signaling, 14(2), 201-211 (2018)
Jiqin Wu et al.
Cell reports, 37(4), 109882-109882 (2021-10-16)
Remdesivir (RDV), a nucleotide analog with broad-spectrum features, has exhibited effectiveness in COVID-19 treatment. However, the precise working mechanism of RDV when targeting the viral RNA-dependent RNA polymerase (RdRP) has not been fully elucidated. Here, we solve a 3.0-Å structure
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.