X4002
Xanthine
≥99%, synthetic (organic), powder
동의어(들):
2,6-Dihydroxypurine
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C5H4N4O2
CAS 번호:
Molecular Weight:
152.11
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
200-718-6
MDL number:
Beilstein/REAXYS Number:
8733
Assay:
≥99%
Biological source:
synthetic (organic)
Form:
powder
Solubility:
1 M NaOH: 0.1 M, clear, colorless to light yellow
제품 이름
Xanthine, BioUltra, ≥99%
InChI key
LRFVTYWOQMYALW-UHFFFAOYSA-N
InChI
1S/C5H4N4O2/c10-4-2-3(7-1-6-2)8-5(11)9-4/h1H,(H3,6,7,8,9,10,11)
SMILES string
O=C1NC(=O)c2nc[nH]c2N1
biological source
synthetic (organic)
product line
BioUltra
assay
≥99%
form
powder
impurities
≤0.0005% Phosphorus (P), ≤0.1% Insoluble matter
ign. residue
≤0.1%
solubility
1 M NaOH: 0.1 M, clear, colorless to light yellow
anion traces
sulfate (SO42-): <0.05%
cation traces
Al: ≤0.0005%, Ca: ≤0.0005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Mg: ≤0.0005%, NH4+: ≤0.05%, Na: ≤0.005%, Pb: ≤0.001%, Zn: ≤0.0005%
Quality Level
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General description
Xanthine is a purine that can be produced in the purine metabolic pathway via different precursors:
- Guanine deamination by guanine deaminase
- Hypoxanthine conversion by xanthine oxidoreductase
Xanthine or its derivatives are naturally present in animal organs, yeast, potatoes, coffee beans, and tea.
Application
Xanthine has been used as a substrate for the determination of xanthine oxidase (XOD) inhibitory activity. It has also been used in the following systems:
- yeast culture
- human cell line culture
- recombinant viruses cloned as bacterial artificial chromosomes in Escherichia coli
Biochem/physiol Actions
Xanthine and xanthine oxidase are used to generate superoxide radicals to measure the activity of superoxide dismutase.
Features and Benefits
- Tested for trace metal content (fuller details in Properties section and on Specification Sheet)
- Tested for trace sulfate content (fuller details in Properties section and on Specification Sheet)
저장 등급
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Insights from multispectral and molecular docking investigation on the xanthine oxidase inhibition by 1, 4-dicaffeoylquinic acid
Cao W, et al.
Journal of Molecular Structure, 1219, 128475-128475 null
Optimization of total phenolic contents, antioxidant, and in-vitro xanthine oxidase inhibitory activity of sunflower head
Mehmood A, et al.
CYTA-journal of Food, 16, 957-964 null
Resistance of postharvest biocontrol yeasts to oxidative stress: a possible new mechanism of action.
Raffaello Castoria et al.
Phytopathology, 93(5), 564-572 (2008-10-24)
ABSTRACT We detected the generation of the reactive oxygen species (ROS) superoxide anion ( O.(-) (2)) and hydrogen peroxide (H(2)O(2)) in apple wounds 2 immediately after wounding, and assessed the relationships between (i) timely colonization of apple wounds by biocontrol
Avery G Frey et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(22), 8031-8036 (2014-05-21)
Although cells express hundreds of metalloenzymes, the mechanisms by which apoenzymes receive their metal cofactors are largely unknown. Poly(rC)-binding proteins PCBP1 and PCBP2 are multifunctional adaptor proteins that bind iron and deliver it to ferritin for storage or to prolyl
Ken Okamoto et al.
Current pharmaceutical design, 19(14), 2606-2614 (2012-11-03)
Xanthine oxidoreductase (XOR), a complex flavoprotein, catalyzes the metabolic reactions leading from hypoxanthine to xanthine and from xanthine to urate, and both reactions take place at the molybdenum cofactor. The enzyme is a target of drugs for therapy of gout
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Instructions
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