X7375
Xanthine
≥99%, synthetic (organic), powder
동의어(들):
2,6-Dihydroxypurine
조직 및 계약 가격을 보려면 로그인를 클릭합니다.
크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C5H4N4O2
CAS 번호:
Molecular Weight:
152.11
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
200-718-6
MDL number:
Beilstein/REAXYS Number:
8733
Assay:
≥99%
Biological source:
synthetic (organic)
Form:
powder
Solubility:
1 M NaOH: soluble 50 mg/mL, clear to slightly hazy, NH4OH: freely soluble, NaOH: freely soluble
제품 이름
Xanthine, ≥99%
InChI key
LRFVTYWOQMYALW-UHFFFAOYSA-N
InChI
1S/C5H4N4O2/c10-4-2-3(7-1-6-2)8-5(11)9-4/h1H,(H3,6,7,8,9,10,11)
SMILES string
O=C1NC(=O)c2nc[nH]c2N1
biological source
synthetic (organic)
assay
≥99%
form
powder
solubility
1 M NaOH: soluble 50 mg/mL, clear to slightly hazy, NH4OH: freely soluble, NaOH: freely soluble
Quality Level
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General description
Xanthine is synthesized from guanine in the presence of guanine deaminase. Xanthine oxidase catalyzes the production of xanthine from hypoxanthine and its subsequent breakdown to uric acid. Xanthine derivatives are present in coffee, tea and cocoa seeds. Xanthine has been proposed as a lead for the generation of pharmacologically active compounds.
Application
Xanthine has been used in a nonradiolabled substrate mix in an Aspergillus nidulans transport assay. It has also been used as a substrate for xanthine oxidase for superoxide anion generation in gill cells and algal cells.
Biochem/physiol Actions
A high level of xanthine is implicated in metabolic disorders like Lesch-Nyhan syndrome. A xanthine-based biosensor may be useful for detecting xanthine in food and clinical samples. Blood and urine samples of patients with renal failure, gout and xanthinuria show high levels of xanthine.
저장 등급
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Study on detection methods for xanthine in food and biological samples
Wu S, et al.
Int. J. Curr. Res. Chem. Pharma. Sci, 3(8), 1-5 (2016)
Transport Assays in Aspergillus nidulans
Krypotou E and Diallinas G
Molecular Microbiology, 3(22), 1-5 (2013)
Biosensing methods for xanthine determination: a review
Pundir CS and Devi R
Enzyme and Microbial Technology, 57, 55-62 (2014)
D L Krebs et al.
Methods in cell science : an official journal of the Society for In Vitro Biology, 21(1), 57-68 (2000-03-25)
Murine B cell lines such as WEHI-231, BAL17 and M12.4.1 are frequently used as model systems to study signal transduction, cell cycle regulation, and apoptosis. Dissection of these processes often involves expressing exogenous genes in these cells. Electroporation is an
Xanthine scaffold: scope and potential in drug development
Singh N, et al.
Heliyon, 4(10), e00829-e00829 (2018)
문서
Uric acid present in animal sera impacts serum-supplemented classical cell culture systems, influencing cell culture performance.
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