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Merck

1279804

USP

Fluoxetine hydrochloride

United States Pharmacopeia (USP) Reference Standard

동의어(들):

(±)-N-Methyl-γ-[4-(trifluoromethyl)phenoxy]benzenepropanamine hydrochloride, LY-110,140 hydrochloride, Prozac®

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C17H18F3NO · HCl
CAS 번호:
Molecular Weight:
345.79
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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제품 이름

Fluoxetine hydrochloride, United States Pharmacopeia (USP) Reference Standard

InChI

1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H

SMILES string

CNCCC(C1=CC=CC=C1)OC2=CC=C(C(F)(F)F)C=C2.[H]Cl

InChI key

GIYXAJPCNFJEHY-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

fluoxetine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

Gene Information

human ... SLC6A4(6532)

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Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Fluoxetine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Fluoxetine Tablets
  • Fluoxetine Delayed-Release Capsules
  • Olanzapine and Fluoxetine Capsules
  • Fluoxetine Oral Solution
  • Fluoxetine Capsules

Biochem/physiol Actions

Selective serotonin reuptake inhibitor; antidepressant.

Legal Information

Sold under license from Eli Lilly and Company.
Prozac is a registered trademark of Eli Lilly and Co.

Other Notes

Sales restrictions may apply.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - STOT RE 2 - STOT SE 3

target_organs

Central nervous system

저장 등급

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable


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시험 성적서(COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our 문서 section.

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

R J Gonzalez-Rothi et al.
Chest, 107(6), 1763-1765 (1995-06-01)
We describe a patient who developed progressive dyspnea, lung infiltrates, and restrictive lung disease in association with the antidepressant fluoxetine hydrochloride (Prozac). The pathologic findings were consistent with hypersensitivity pneumonitis. An associated pulmonary phospholipidosis was also noted.
Sean C Godar et al.
Journal of psychiatric research, 56, 1-9 (2014-06-03)
The termination of serotonin (5-hydroxytryptamine, 5-HT) neurotransmission is regulated by its uptake by the 5-HT transporter (5-HTT), as well as its degradation by monoamine oxidase (MAO)-A. MAO-A deficiency results in a wide set of behavioral alterations, including perseverative behaviors and
Paulina Jedynak et al.
Journal of psychiatric research, 56, 106-111 (2014-06-17)
The neurogenesis hypothesis of major depression has two main facets. One states that the illness results from decreased neurogenesis while the other claims that the very functioning of antidepressants depends on increased neurogenesis. In order to verify the latter, we
Rody Kingston et al.
PLoS genetics, 17(11), e1009885-e1009885 (2021-11-05)
Molecular insights into the selective vulnerability of retinal ganglion cells (RGCs) in optic neuropathies and after ocular trauma can lead to the development of novel therapeutic strategies aimed at preserving RGCs. However, little is known about what molecular contexts determine
Melody V Wu et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 39(8), 1861-1871 (2014-02-13)
Adult hippocampal neurogenesis is critically implicated in rodent models of stress and anxiety as well as behavioral effects of antidepressants. Whereas similar factors such as psychiatric disorder and antidepressant administration are correlated with hippocampal volume in humans, the relationship between

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