465119
Baicalein
98%
Sinónimos:
5,6,7-Trihydroxyflavone
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Fórmula empírica (notación de Hill):
C15H10O5
Número CAS:
Peso molecular:
270.24
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
272683
Assay:
98%
Form:
solid
Servicio técnico
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Permítanos ayudarleQuality Level
assay
98%
form
solid
mp
256-271 °C (lit.)
functional group
ketone, phenyl
SMILES string
Oc1cc2OC(=CC(=O)c2c(O)c1O)c3ccccc3
InChI
1S/C15H10O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-7,17-19H
InChI key
FXNFHKRTJBSTCS-UHFFFAOYSA-N
Gene Information
mouse ... Hexa(15211)
rat ... Alox15(81639), Alox5(25290)
General description
Baicalein, a flavonoid, is a xanthine oxidase inhibitor. Anti-inflammatory effects of baicalein in peripheral human leukocytes has been studied.
Application
Baicalein was used in a study to investigate the in vitro quantitative inhibition of lipoxygenase.
Biochem/physiol Actions
The flavonoid component of Nepalese and Sino-Japanese crude drugs. Baicalein, a major flavone of Scutellariae baicalensis, inhibits the 12-lipoxygenase (12-LOX) pathway of arachidonic acid metabolism, which inhibits cancer cell proliferation and induces apoptosis.
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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