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850368P

Avanti

20:0 PC

Avanti Research™ - A Croda Brand

Sinónimos:

1,2-dieicosanoyl-sn-glycero-3-phosphocholine; PC(20:0/20:0)

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Fórmula empírica (notación de Hill):
C48H96NO8P
Número CAS:
61596-53-0
Peso molecular:
846.25
MDL number:
MFCD00067533
UNSPSC Code:
51191904
NACRES:
NA.25
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Nombre del producto

20:0 PC, 1,2-diarachidoyl-sn-glycero-3-phosphocholine, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 200 mg (850368P-200mg), pkg of 1 × 25 mg (850368P-25mg), pkg of 1 × 500 mg (850368P-500mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850368P

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCCCC)=O)=O

InChI

1S/C48H96NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-40-47(50)54-44-46(45-56-58(52,53)55-43-42-49(3,4)5)57-48(51)41-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h46H,6-45H2,1-5H3/t46-/m1/s1

InChI key

YKIOPDIXYAUOFN-YACUFSJGSA-N

General description

Phosphatidylcholine, a major source of diacylglycerol (DAG) is considered as a biological membrane lipid. 20:0 PC is a zwitterionic lipid.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

20:0 PC may be used:
  • in the preparation of liposomes
  • to prepare vesicles or supported bilayer to study its ability in spontaneously forming distinct lipid domains, rafts and/or asymmetric bilayers along with other phosphatidylcholine lipids
  • to prepare small unilamellar vesicles (SUVs) to study the effect of hydrophobic mismatch on gramicidin conformation and organization

Biochem/physiol Actions

Phosphatidylcholine (PC) can serve as a surfactant in the mucus.

Packaging

20 mL Clear Glass Screw Cap Vial (850368P-500mg)
5 mL Amber Glass Screw Cap Vial (850368P-200mg)
5 mL Amber Glass Screw Cap Vial (850368P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Markus Ritter et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 32(1), 46-52 (2013-07-23)
We investigated if mixtures of the phosphatidylcholine (PC) lipids 1,2-dilauroyl-sn-glycero-3-phosphocholine (C12:0 PC; DLPC) and 1,2-diarachidoyl-sn-glycero-3-phosphocholine (C20:0 PC; DAPC), which differ by eight methylene groups in acyl chain length, lead to the spontaneous formation of distinct lipid rafts and asymmetric bilayers.
Second Messengers
Cell Biology, 443-462 (2017)
Inflammatory Bowel Disease
Integrative Medicine, 501-516 (2018)
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