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Merck

850464C

Avanti

18:0-14:0 PC

Avanti Research - A Croda Brand

Sinónimos:

1-octadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphocholine; SMPC; PC(18:0/14:0)

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Fórmula empírica (notación de Hill):
C40H80NO8P
Número CAS:
Peso molecular:
734.04
MDL number:
NACRES:
NA.25
UNSPSC Code:
51191904
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Nombre del producto

18:0-14:0 PC, 1-stearoyl-2-myristoyl-sn-glycero-3-phosphocholine, chloroform

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850464C-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand 850464C

concentration

10 mg/mL (850464C-25mg)

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

General description

Phosphatidylcholine (PC) is a major bilayer-forming phospholipid in which the headgroup carries a positively and negatively charged quaternary amine and a phosphate, respectively.

Application

18:0-14:0 PC (1-stearoyl-2-myristoyl-sn-glycero-3-phosphocholine) may be used in liposomes to study its interference in the proliferation of several cell lines using transmission electron microscopy (TEM).

Biochem/physiol Actions

Phosphatidylcholine (PC) can form a hydrophobic surface in the mucus by acting as a surfactant to inhibit the penetrance of bacteria.

Packaging

5 mL Clear Glass Sealed Ampule (850464C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

wgk

WGK 3

Clase de almacenamiento

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

flash_point_f

does not flash

flash_point_c

does not flash



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Lipid-Protein Interactions in Membranes
The Membranes of Cells, 291-334 (2016)
Inflammatory Bowel Disease
Integrative Medicine, 501-516 (2018)
Anna Werlein et al.
Biochimica et biophysica acta, 1848(7), 1599-1608 (2015-04-29)
According to early experiments with natural extracts, phosphatidylcholines (PCs) are widely considered essentially non-toxic. In addition to these physiological mixed-chain PCs, many different synthetic diacyl-PCs are currently available, but they have never been systematically evaluated for any interference with cell