Saltar al contenido
Merck

PHR1214

Methyl salicylate

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

2-Hydroxybenzoic acid methyl ester, Methyl 2-hydroxybenzoate, Oil of wintergreen, Wintergreen oil

Iniciar sesión para ver los precios por organización y contrato.

Seleccione un Tamaño

Acerca de este artículo

Fórmula lineal:
2-(HO)C6H4CO2CH3
Número CAS:
119-36-8
Peso molecular:
152.15
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329823221
EC Number:
204-317-7
Beilstein/REAXYS Number:
971516
MDL number:
MFCD00002214

Documentos clave

Ver Toda la documentación
Servicio técnico
¿Necesita ayuda? Nuestro equipo de científicos experimentados está aquí para ayudarle.
Permítanos ayudarle
Servicio técnico
¿Necesita ayuda? Nuestro equipo de científicos experimentados está aquí para ayudarle.
Permítanos ayudarle

InChI key

OSWPMRLSEDHDFF-UHFFFAOYSA-N

InChI

1S/C8H8O3/c1-11-8(10)6-4-2-3-5-7(6)9/h2-5,9H,1H3

SMILES string

COC(=O)c1ccccc1O

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1537450

vapor density

5.26 (vs air)

vapor pressure

1 mmHg ( 54 °C)

API family

methyl salicylate

CofA

current certificate can be downloaded

autoignition temp.

847 °F

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

refractive index

n20/D 1.536 (lit.)

bp

222 °C (lit.)

mp

−8-−7 °C (lit.)

density

1.174 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Quality Level

300

¿Está buscando productos similares? Visita Guía de comparación de productos

Categorías relacionadas

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Methyl salicylate is one of the common ingredients present in topical analgesics and rubifacients. It is prescribed for the management of minor muscle aches and pains.

Application

Methyl salicylate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography and voltammetry techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC3556 in the slot below. This is an example certificate only and may not be the lot that you receive.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Repr. 2 - Skin Sens. 1B

Clase de almacenamiento

10 - Combustible liquids

wgk

WGK 2

flash_point_f

204.8 °F - closed cup

flash_point_c

96 °C - closed cup

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Optimization and validation of liquid chromatography and headspace-gas chromatography based methods for the quantitative determination of capsaicinoids, salicylic acid, glycol monosalicylate, methyl salicylate, ethyl salicylate, camphor and l-menthol in a topical formulation
Pauwels J, et al.
Journal of Pharmaceutical and Biomedical Analysis, 60(3), 51-58 (2012)
Fourier transform mid-infrared (MIR) and near-infrared (NIR) spectroscopy for rapid quality assessment of Chinese medicine preparation Honghua Oil
Wu YW, et al.
Journal of Pharmaceutical and Biomedical Analysis, 46(3), 498-504 (2008)
Determination of salicylic acid in pharmaceutical formulations and foods by differential-pulse voltammetry using a glassy carbon electrode
Fung YS and Luk SF
Analyst, 114(8), 943-945 (1989)
Agata Bartyzel et al.
Analytica chimica acta, 707(1-2), 204-209 (2011-10-27)
N,N'-bis-(α-methylsalicylidene)-2,2-dimethyl-1,3-propanediimine (SBTD) modified silica gel was prepared and used as sorbent for solid phase extraction of Cr(III) ions from aqueous solution. This sorbent showed a high sorption affinity for Cr(III) while recovery of Cr(VI) was very low. The analyte ion
J S Valdez et al.
Journal of chromatography. B, Biomedical sciences and applications, 729(1-2), 163-171 (1999-07-20)
Analytical methods using gas chromatography-flame ionization detection (GC-FID) for the quantitation of camphor and menthol and GC-MS for the quantitation of methyl salicylate have been developed for measurement of low concentrations from human plasma. Anethole serves as the internal standard
Ver todos los artículos relacionados

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico