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Merck

PHR1472

Tartaric Acid

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

L-(+)-Tartaric acid, (2R,3R)-(+)-Tartaric acid, L-Threaric acid

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Fórmula lineal:
HO2CCH(OH)CH(OH)CO2H
Número CAS:
87-69-4
Peso molecular:
150.09
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329823401
EC Number:
201-766-0
Beilstein/REAXYS Number:
1725147
MDL number:
MFCD00064207

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InChI key

FEWJPZIEWOKRBE-JCYAYHJZSA-N

InChI

1S/C4H6O6/c5-1(3(7)8)2(6)4(9)10/h1-2,5-6H,(H,7,8)(H,9,10)/t1-,2-/m1/s1

SMILES string

O[C@H]([C@@H](O)C(O)=O)C(O)=O

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1643340

vapor density

5.18 (vs air)

API family

tartaric acid

CofA

current certificate can be downloaded

autoignition temp.

797 °F

packaging

pkg of 1 g

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

170-172 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

300

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Categorías relacionadas

General description

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards
Tartaric Acid belongs to the group of carboxylic acids, and is abundantly found in grapes and wine. It is widely used in drugs, food, and beverage industry.

Application

Tartaric Acid may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using stopped-flow chemiluminescence spectrometry.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC1695 in the slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H318

Hazard Classifications

Eye Dam. 1

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Sensitive determination of periodate and tartaric acid by stopped-flow chemiluminescence spectrometry
Gaikwad A, et al.
Analyst, 119(8), 1819-1824 (1994)
Sho Isoyama et al.
Cancer science, 106(2), 171-178 (2014-12-09)
Drug resistance often critically limits the efficacy of molecular targeted drugs. Although pharmacological inhibition of phosphatidylinositol 3-kinase (PI3K) is an attractive therapeutic strategy for cancer therapy, molecular determinants for efficacy of PI3K inhibitors (PI3Kis) remain unclear. We previously identified that
Encyclopaedia of Occupational Health and Safety: Industries and Occupations, 4(8), 1819-1824 (1998)
Enological Chemistry, 4(8), 1819-1824 (2012)
Miyako Yoshida et al.
Chemical & pharmaceutical bulletin, 62(12), 1252-1258 (2014-12-03)
The objective of this study was to evaluate an improved bitterness sensor which has been developed to allow the precise and sensitive prediction of the bitterness of acidic bitter pharmaceutical active ingredients, using as examples nine non-steroidal anti-inflammatory drugs (NSAIDs).
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