PHR1582

Dehydroacetic acid

Name: Dehydroacetic acid
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

Dehydroacetic acid, 2-Acetyl-5-hydroxy-3-oxo-4-hexenoic acid δ-lactone

Iniciar sesión para ver los precios por organización y contrato.

Seleccione un Tamaño

Todas las fotos(1)

About This Item

Fórmula empírica (notación de Hill):

C₈H₈O₄

Número CAS:

520-45-6

Peso molecular:

168.15

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329823490

EC Number:

208-293-9

Beilstein/REAXYS Number:

6129

MDL number:

MFCD00066709

Nombre del producto

Dehydroacetic acid, Pharmaceutical Secondary Standard; Certified Reference Material

Quality Level

300

InChI key

PGRHXDWITVMQBC-UHFFFAOYSA-N

InChI

1S/C8H8O4/c1-4-3-6(10)7(5(2)9)8(11)12-4/h3,7H,1-2H3

SMILES string

CC(=O)C1C(=O)OC(C)=CC1=O

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to USP 1166309

API family

dehydroacetic acid

CofA

current certificate can be downloaded

packaging

pkg of 1 g

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

bp

270 °C (lit.)

mp

111-113 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

¿Está buscando productos similares? Visita Guía de comparación de productos

Categorías relacionadas

Analytical Reference Materials for Pharma QC

Certified Reference Materials

Pharmacopeia & Metrological Institute Standards

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Application

Dehydroacetic acid may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical, food and cosmetic formulations by chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

General description

Dehydroacetic acid is a pyrone derivative, that is typically synthesized by the base-catalyzed dimerization of diketene. It is used as a preservative in pharmaceutical, food and cosmetic products.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAA4498 in the slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Clase de almacenamiento

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

314.6 °F

flash_point_c

157 °C

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Simultaneous determination of sorbic acid, dehydroacetic acid and benzoic acid by gas chromatography-mass spectrometry

Kakemoto M

Journal of Chromatography A, 594(1-2), 253-257 (1992)

Comparing micellar electrokinetic chromatography and microemulsion electrokinetic chromatography for the analysis of preservatives in pharmaceutical and cosmetic products

Huang HY, et al.

Journal of Chromatography A, 993(1-2), 153-164 (2003)

Dehydroacetic acid, triacetic acid lactone, and related pyrones

Advances in Heterocyclic Chemistry, 53, 1-84 (1992)

Simultaneous determination of nine kinds of preservatives in foods by HPLC

Kishi H and Yamada T

Journal of Food Hygiene and Safety, 48(3), 58-63 (2007)

Simultaneous analysis of dehydroacetic acid, benzoic acid, sorbic acid and salicylic acid in cosmetic products by solid-phase extraction and high-performance liquid chromatography.

E Mikami et al.

Journal of pharmaceutical and biomedical analysis, 28(2), 261-267 (2002-04-04)

A high-performance liquid chromatographic (HPLC) method for simultaneous determination of dehydroacetic acid (DHA), benzoic acid (BA), sorbic acid (SOA) and salicylic acid (SA) was developed for application to cosmetic products. Isocratic reversed-phase HPLC was employed for quantitative analysis using tetra-n-butylammonium

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico