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Fórmula empírica (notación de Hill):
C12H17NO2
Número CAS:
Peso molecular:
207.27
UNSPSC Code:
41116107
NACRES:
NA.24
MDL number:
Servicio técnico
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pharmaceutical primary standard
API family
ciclopirox
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
SMILES string
ON1C(C2CCCCC2)=CC(C)=CC1=O
InChI
1S/C12H17NO2/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10/h7-8,10,15H,2-6H2,1H3
InChI key
SCKYRAXSEDYPSA-UHFFFAOYSA-N
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Ciclopirox EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
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M Bohn et al.
Journal of the American Academy of Dermatology, 43(4 Suppl), S57-S69 (2000-10-29)
Ciclopirox is a synthetic hydroxypyridone antifungal agent. In contrast to the azoles, glucuronidation is the main metabolic pathway of ciclopirox; therefore interactions with drugs metabolized via the cytochrome P450 system are unlikely Ciclopirox is also distinct from the common systemic
A K Gupta et al.
Journal of the American Academy of Dermatology, 43(4 Suppl), S96-102 (2000-10-29)
Ciclopirox nail lacquer solution 8% has been shown to be effective in the treatment of dermatophyte onychomycosis of mild to moderate severity Other studies report the effectiveness of ciclopirox nail lacquer in onychomycosis caused by Candida sp and nondermatophyte molds.
Aditya K Gupta et al.
International journal of dermatology, 45(1), 66-69 (2006-01-24)
Seborrheic dermatitis is a chronic superficial fungal infection of the skin, particularly affecting sites rich in sebaceous glands. Although the precise etiology of seborrheic dermatitis is uncertain, yeasts of the genus Malassezia are known to play a causative role. Ciclopirox