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Merck

Y0001593

Dexametasona

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

(11β,16α)-9-Fluoro-11,17,21-trihidroxi-16-metilpregna-1,4-dieno-3,20-diona, 9α-Fluoro-16α-metil-11β,17α,21-trihidroxi-1,4-pregnadieno-3,20-diona, 9α-fluoro-16α-metilprednisolona, Prednisolona F

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About This Item

Fórmula empírica (notación de Hill):
C22H29FO5
Número CAS:
50-02-2
Peso molecular:
392.46
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329831500
MDL number:
MFCD00064136
Beilstein/REAXYS Number:
2066651

Nombre del producto

Dexametasona, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1

SMILES string

C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO

InChI key

UREBDLICKHMUKA-CXSFZGCWSA-N

biological source

synthetic

grade

pharmaceutical primary standard

agency

EP

API family

dexamethasone

form

powder

manufacturer/tradename

EDQM

storage condition

protect from light

mp

262-264 °C (lit.)
262-264 °C

solubility

water: <0.1 g/L

application(s)

pharmaceutical (small molecule)

format

neat

shipped in

ambient

storage temp.

2-8°C

Gene Information

human ... NR3C1(2908)

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Categorías relacionadas

Biochem/physiol Actions

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Application

Dexamethasone is used as an EP referencs standard to quantify the analyte in pharmaceutical formulations using liquid chromatography (LC) technique.

General description

Dexamethasone belongs to the class of synthetic glucocorticoid steroid drugs.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H360FD

Hazard Classifications

Repr. 1B

Clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number

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Visite la Librería de documentos

Dexamethasone: Therapeutic Uses, Mechanism of Action and Potential Side Effects (2013)
Dexamethasone
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 10(3), 4961-4963 (2021)
Sara Bringhen et al.
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