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C1768

Cytarabine

≥90% (HPLC), crystalline, DNA replication inhibitor

Sinónimos:

(β-D-Arabinofuranosyl)cytosine, Ara-C, Arabinocytidine, Arabinosylcytosine, Cytarabine, Cytosine arabinoside

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Fórmula empírica (notación de Hill):
C9H13N3O5
Número CAS:
147-94-4
Peso molecular:
243.22
NACRES:
NA.77
PubChem Substance ID:
24892435
UNSPSC Code:
12352200
EC Number:
205-705-9
MDL number:
MFCD00066487
Beilstein/REAXYS Number:
89175
Assay:
≥90% (HPLC)
Form:
crystalline
Quality level:
200
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Nombre del producto

Cytosine β-D-arabinofuranoside, crystalline, ≥90% (HPLC)

Quality Level

200

assay

≥90% (HPLC)

form

crystalline

storage temp.

2-8°C

SMILES string

NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O

InChI

1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7+,8-/m1/s1

InChI key

UHDGCWIWMRVCDJ-CCXZUQQUSA-N

Gene Information

human ... POLA1(5422), POLA2(23649), POLB(5423), POLD1(5424), POLD2(5425), POLD3(10714), POLD4(57804), POLE(5426), POLE2(5427), POLE3(54107), PRIM1(5557), PRIM2(5558)
mouse ... Cda(72269)

Biochem/physiol Actions

Ara-C incorporates into DNA and inhibits DNA replication by forming cleavage complexes with topoisomerase I resulting in DNA fragmentation; does not inhibit RNA synthesis. Anti-leukemia agent.

Features and Benefits

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

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pictograms

Health hazard
GHS08

signalword

Danger

Hazard Classifications

Muta. 1B - Repr. 2

Clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

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Certificados de análisis (COA)

Lot/Batch Number
0000518471
0000518471
0000505207
0000505205
0000505204

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