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Merck

E6511

Ethylenediaminetetraacetic acid tetrasodium salt dihydrate

BioReagent, suitable for cell culture, 98.5-102.0%

Sinónimos:

EDTA tetrasodium salt, Edathamil, Tetrasodium ethylenediaminetetraacetate dihydrate

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About This Item

Fórmula lineal:
(NaOOCCH2)2NCH2CH2N(CH2COONa)2 · 2H2O
Número CAS:
Peso molecular:
416.20
UNSPSC Code:
12352204
NACRES:
NA.75
PubChem Substance ID:
EC Number:
200-573-9
Beilstein/REAXYS Number:
3861753
MDL number:

Nombre del producto

Ethylenediaminetetraacetic acid tetrasodium salt dihydrate, BioReagent, suitable for cell culture, 98.5-102.0%

InChI

1S/C10H16N2O8.4Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;;;2*1H2/q;4*+1;;/p-4

InChI key

KSYNLCYTMRMCGG-UHFFFAOYSA-J

SMILES string

O.O.[Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC([O-])=O

product line

BioReagent

assay

98.5-102.0%

form

powder

technique(s)

cell culture | mammalian: suitable

solubility

H2O: 160 mg/mL

shipped in

ambient

storage temp.

room temp

Quality Level

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Application

Ethylenediaminetetraacetic acid tetrasodium salt dihydrate has been used:
  • as a chelating agent to isolate human endometrial stem cell/stromal cells (hEnSCs) from menstrual blood
  • as a chelator in animal and testicular cell isolation
  • as a chelator for the culture of neural stem cells

Biochem/physiol Actions

Ethylenediaminetetraacetic acid (EDTA) is used to eliminate enzyme inhibition by traces of heavy metals, and to inhibit enzymes that require divalent cations as cofactors.

General description

Ethylenediaminetetraacetic acid (EDTA) is a chelator of metal ions. It is a substituted diamine, which has antibacterial activity. EDTA removes the undesirable effects of ferric, cupric and manganic ions in bleaching. It prevents cellular division, chlorophyll synthesis and algal biomass production. EDTA is an inhibitor of metalloprotease. It has anticoagulant property.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - STOT RE 2

target_organs

Respiratory Tract

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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What is the best protocol to cryopreserve immature mouse testicular cell suspensions?
Onofre J, et al.
Reproductive Biomedicine Online, 37(1), 6-17 (2018)
Human Endometrial Stem Cell Isolation from Endometrium and Menstrual Blood
Tavakol S, et al.
Bio-protocol, 8(2) (2018)
Modulation of matrix metalloproteinase activity by EDTA prevents posterior capsular opacification
Hazra S, et al.
Molecular Vision, 18(6), 1701-1701 (2012)
Accurate Results in the Clinical Laboratory: A Guide to Error Detection and Correction (2013)
Gitte Lund et al.
International archives of allergy and immunology, 153(4), 323-334 (2010-06-19)
Allergen-specific immunotherapy (SIT) leads to reduced symptoms upon allergen exposure through as yet unresolved mechanisms. Desensitization of basophils to specific allergens during the updosing phase of injection immunotherapy may contribute to the clinical effect of SIT. Here we report a

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