G6776
Genistein
From Glycine max (soybean), ~98% (HPLC), tyrosine protein kinase inhibitor, powder
Sinónimos:
4′,5,7-Trihydroxyisoflavone, 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
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Nombre del producto
Genistein, from Glycine max (soybean), ~98% (HPLC)
biological source
Glycine max (soybean)
Quality Level
assay
~98% (HPLC)
form
powder
mp
>280 °C
solubility
DMSO: soluble, ethanol: soluble
storage temp.
−20°C
SMILES string
Oc1ccc(cc1)C2=COc3cc(O)cc(O)c3C2=O
InChI
1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H
InChI key
TZBJGXHYKVUXJN-UHFFFAOYSA-N
Gene Information
human ... AKT1(207), CYP19A1(1588), EGFR(1956), ESR1(2099), ESR2(2100)
mouse ... Esr1(13982), Hexa(15211)
rat ... Adora1(29290), Adora2a(25369), Ar(24208)
General description
Application
- as an anticancer agent to test its cytotoxicity in cervix adenocarcinoma cells
- as a polyphenol to test its effect on reactive oxygen species in mitochondria from sperm
- to test its radical scavenging effect on the UV irradiated in dermal and keloid fibroblasts
Biochem/physiol Actions
Features and Benefits
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type N95 (US)
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