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Merck

1012553

USP

Albendazole

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

Methyl 5-(propylthio)-2-benzimidazolecarbamate

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Fórmula empírica (notación de Hill):
C12H15N3O2S
Número CAS:
Peso molecular:
265.33
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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InChI key

HXHWSAZORRCQMX-UHFFFAOYSA-N

SMILES string

CCCSc1ccc2[nH]c(NC(=O)OC)nc2c1

InChI

1S/C12H15N3O2S/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)

grade

pharmaceutical primary standard

API family

albendazole

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Albendazole USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Albendazole Oral Suspension
  • Albendazole Tablets

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

pictograms

Health hazardEnvironment

signalword

Warning

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2 Oral

target_organs

Adrenal gland,Blood,male reproductive organs,spleen

Clase de almacenamiento

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable


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J Horton
Annals of tropical medicine and parasitology, 103 Suppl 1, S33-S40 (2009-11-11)
The history of the development of ivermectin and diethylcarbamazine for the treatment of human filarial infections is relatively well known and documented. The story of how albendazole became involved in the global elimination programmes is, however, less well known. This
Matthew E Falagas et al.
The American journal of the medical sciences, 334(3), 171-179 (2007-09-18)
Albendazole has been used in various ways in the treatment of cystic echinococcosis (CE). We reviewed the available evidence regarding the role of albendazole for the treatment of patients with CE. The available comparative clinical trials (randomized or not) that
M E Oxberry et al.
Journal of veterinary pharmacology and therapeutics, 23(3), 113-120 (2000-12-08)
Trophozoites of the protozoan parasite Giardia duodenalis were exposed to various albendazole concentrations for 4 h, washed, fixed and incubated with antibodies raised against albendazole and its two major metabolites albendazole sulphoxide and albendazole sulphone. Tubulin antibodies were also used.
John Horton
Current opinion in infectious diseases, 15(6), 599-608 (2003-06-25)
It is over 25 years ago since the original animal research was conducted into albendazole. This review highlights some important steps in fundamental research and the management of helminth disease that have occurred in the past year, appearing in the
John Horton
Fundamental & clinical pharmacology, 17(2), 205-212 (2003-04-02)
Twenty years after the first cases of echinococcal disease were treated with albendazole, it has become an important component in the overall management of both cystic and alveolar echinococcosis. This paper reviews some of the key steps and issues facing

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