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Merck

1044006

USP

Aspirin

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

Acetylsalicylic acid, 2-Acetoxybenzoic acid, O-Acetylsalicylic acid, ASA, Aspirin

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About This Item

Fórmula lineal:
2-(CH3CO2)C6H4CO2H
Número CAS:
50-78-2
Peso molecular:
180.16
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329749073
MDL number:
MFCD00002430
Beilstein/REAXYS Number:
779271

Nombre del producto

Aspirin, United States Pharmacopeia (USP) Reference Standard

InChI

1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)

SMILES string

CC(=O)Oc1ccccc1C(O)=O

InChI key

BSYNRYMUTXBXSQ-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

aspirin

manufacturer/tradename

USP

mp

134-136 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

Gene Information

human ... PTGS1(5742), PTGS2(5743)

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Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Aspirin USP reference standard suitable for use in specified USP compendial quality tests and assays.

Also used to prepare standard solution for impurity analysis and performance test according to the given below monographs of United States Pharmacopeia (USP):
  • Carisoprodol and Aspirin Tablets.
  • Aspirin Tablets.
  • Aspirin Boluses.
  • Butalbital, Aspirin, Caffeine, and Codeine Phosphate Capsules.

Biochem/physiol Actions

Blocks the production of prostaglandins by inhibiting cyclooxygenase (prostaglandin H synthase), with greater selectivity toward the COX-1 isoform. The antithrombotic effect is due to the inhibition of COX-1 in platelets that blocks thromboxane production and platelet aggregation. Chemopreventive against colorectal and other solid tumors.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 1

flash_point_f

482.0 °F

flash_point_c

250 °C

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Certificados de análisis (COA)

Lot/Batch Number

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Visite la Librería de documentos

Butalbital, Aspirin, Caffeine, and Codeine Phosphate Capsules
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 46(2), 648-648 (2013)
Aspirin Tablets
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 42(4), 392-392 (2020)
Carisoprodol and Aspirin Tablets
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 778-778 (2013)
Aspirin Boluses
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 42(4), 388-388 (2017)
Yu-Chi Tung et al.
Medical care, 52(6), 519-527 (2014-05-03)
A volume-outcome relationship has been found for acute myocardial infarction (AMI); however, the mechanisms underlying the relationship remain unclear. In particular, it is not known whether processes of care are mediators of the volume-outcome relationship, that is, whether the mechanisms
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