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Merck

1335508

USP

Ibuprofen

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

p-Isobutylhydratropic acid, Benzeneacetic acid, α-Methyl-4-(isobutyl)phenylacetic acid, (±)-2-(4-Isobutylphenyl)propanoic acid

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Fórmula empírica (notación de Hill):
C13H18O2
Número CAS:
Peso molecular:
206.28
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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grade

pharmaceutical primary standard

API family

ibuprofen

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CC(C)Cc1ccc(cc1)C(C)C(O)=O

InChI

1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)

InChI key

HEFNNWSXXWATRW-UHFFFAOYSA-N

Gene Information

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ibuprofen USP reference standard suitable for use in specified USP compendial tests and assays.

Also used to prepare standard preparation, standard and standard stock solution for performance tests, assay, identification, and impurity analysis according to the given below monographs of United States Pharmacopeia (USP):
  • Diphenhydramine Hydrochloride and Ibuprofen Capsules
  • Ibuprofen and Pseudoephedrine Hydrochloride Tablets

Biochem/physiol Actions

Cyclooxygenase (COX) inhibitor that has greater activity against COX-1 than against COX-2.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.


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Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Clase de almacenamiento

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable



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Ibuprofen and Pseudoephedrine Hydrochloride Tablets
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 2286-2286 (2013)
Diphenhydramine Hydrochloride and Ibuprofen Capsules
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 41(2), 1431-1431 (2020)
Yexuan Mao et al.
Talanta, 132, 894-901 (2014-12-06)
The fundamental studies for the binding events of protein and its partner are crucial in drug development. In this study, a novel technology named microscale thermophoresis (MST) was applied in the investigation of molecular interaction between an organic dye fluorescein