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Merck

1453005

USP

Naloxone

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

(5α)-4,5-Epoxy-3,14-dihydroxy-17-(2-propen-1-yl)morphinan-6-one

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About This Item

Fórmula empírica (notación de Hill):
C19H21NO4
Número CAS:
465-65-6
Peso molecular:
327.37
MDL number:
MFCD00242634
UNSPSC Code:
41116107
NACRES:
NA.24

Nombre del producto

Naloxone, United States Pharmacopeia (USP) Reference Standard

SMILES string

N1([C@H]2[C@]3([C@@]4([C@@H](Oc5c4c(ccc5O)C2)C(=O)CC3)CC1)O)CC=C

InChI

1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1

InChI key

UZHSEJADLWPNLE-GRGSLBFTSA-N

grade

pharmaceutical primary standard

API family

naloxone

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Categorías relacionadas

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Naloxone USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Naloxone Hydrochloride
  • Naloxone Hydrochloride Injection
  • Pentazocine and Naloxone Tablets
  • Buprenorphine and Naloxone Sublingual Tablets

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number

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Visite la Librería de documentos

Daisuke Yamada et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 39(8), 1852-1860 (2014-02-13)
Although the underlying mechanism remains unknown, several studies have suggested benefits of n-3 long-chain polyunsaturated fatty acid (PUFA) for patients with anxiety disorders. Elevated fear is thought to contribute to the pathogenesis of particular anxiety disorders. The aim of the
Marco Lanza et al.
British journal of pharmacology, 171(15), 3693-3701 (2014-04-25)
CR4056 is a novel imidazoline-2 (I2 ) ligand exhibiting potent analgesic activity in animal models of pain. In this study, we investigated the effects of CR4056 in a well-established model of postoperative pain where rats develop hyperalgesia in the injured
Naloxone Hydrochloride
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 46(2) (2022)
Buprenorphine and Naloxone Sublingual Tablets
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 42(3), 616-616 (2020)
Pentazocine and Naloxone Tablets
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 45(1), 3463-3463 (2023)
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